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Opinion|Videos|January 22, 2025

Bispecifics in R/R MM: Selecting the Best Bispecific and Optimal Sequencing Strategies

Author(s)Meera Mohan, MD, Areyl Goff, APNP, Hashim Mann, MD

Dr Mohan asks Dr Nadeem about the selection process among bispecific antibodies, the factors influencing decision-making, and the use of talquetamab, teclistamab, or elranatamab in specific patient subgroups, followed by a discussion with Dr Mann on next therapeutic steps if a patient experiences disease progression on talquetamab.

Episodes in this series

EP. 1 John’s Journey with R/R MM

EP. 1 John’s Journey with R/R MM

EP. 2 MonumenTAL: Key Efficacy Outcomes

EP. 2 MonumenTAL: Key Efficacy Outcomes

EP. 3 Implications of Talquetamab on the Current Treatment Landscape for R/R MM

EP. 3 Implications of Talquetamab on the Current Treatment Landscape for R/R MM

EP. 4 Bispecifics in R/R MM: Selecting the Best Bispecific and Optimal Sequencing Strategies

EP. 4 Bispecifics in R/R MM: Selecting the Best Bispecific and Optimal Sequencing Strategies

EP. 5 Eva’s Treatment Journey With R/R MM

EP. 5 Eva’s Treatment Journey With R/R MM

EP. 6 MagnestisMM: Key Efficacy Data and its Clinical Implications

EP. 6 MagnestisMM: Key Efficacy Data and its Clinical Implications

EP. 7 Elranatamab: Real-World Experience and Sequencing

EP. 7 Elranatamab: Real-World Experience and Sequencing

EP. 8 Future of R/R MM: Emerging Agents

EP. 8 Future of R/R MM: Emerging Agents

Video content above is prompted by the following:

How do you approach the selection process among the various available bispecific antibodies?
- What key factors influence your decision?
- In which specific patient subgroups would you lean toward using talquetamab, teclistamab, or elranatamab?
If this patient were to experience disease progression on talquetamab, what would be your next therapeutic approach and why?
- What considerations would guide your decision-making process?

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