Opinion|Videos|January 24, 2025
Overview of the CAR T-Cell Therapy Process: Apheresis, Manufacturing, Potential Bridging Therapies, Lymphodepletion, and Infusion
Panelists discuss how chimeric antigen receptor (CAR) T-cell therapy’s mechanism of action and treatment workflow requires extensive institutional coordination, from patient selection through bridging therapy and infusion, with varied approaches to managing patients during the manufacturing period across different centers.
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Video content above is prompted by the following:
- Could you explain how CAR T-cell therapy works and describe the treatment process?
- Do you consider CAR T therapy a complex process at your institution, or have you been able to streamline the logistics and integration into clinical workflows?
- Dr Usmani to ask Dr Mailankody: Can you explain your institution’s approach to bridging therapy for patients awaiting CAR-T manufacturing and infusion?
- Do you send patients back to community center or does it happen in-house?
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