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Opinion|Videos|January 17, 2025

CAR-T in Earlier Lines of MM Treatment: Patient Eligibility - Considerations between Ide-cel vs. Cilta-cel

Author(s)Saad Z. Usmani, MD, MBA, FACP, Carlyn Rose Tan, MD , Sham Mailankody, MBBS

Panelists discuss how patient selection criteria and individual characteristics help determine whether ide-cel or cilta-cel is the more appropriate chimeric antigen receptor T-cell therapy choice for early-line treatment in patients with multiple myeloma.

Episodes in this series

4 experts are featured in this series.

EP. 1 Highlighted Data Review of CAR-T in Early R/R MM

4 experts are featured in this series.

EP. 2 Expert Insights: Distinguishing between CARTITUDE-4 vs. KarMMa-3 Trials

4 experts are featured in this series.

EP. 3 CAR-T in R/R MM: Patient Selection & Treatment Sequencing

4 experts are featured in this series.

EP. 4 CAR-T in Earlier Lines of MM Treatment: Patient Eligibility - Considerations between Ide-cel vs. Cilta-cel

4 experts are featured in this series.

EP. 5 MSKCC Insights: CAR T Referral Process

4 experts are featured in this series.

EP. 6 Overview of the CAR T-Cell Therapy Process: Apheresis, Manufacturing, Potential Bridging Therapies, Lymphodepletion, and Infusion

4 experts are featured in this series.

EP. 7 Collaboration With Community Colleagues: Comanagement and Transitions of Care

4 experts are featured in this series.

EP. 8 CAR T Referral Process: Challenges Seen and How They Can Be Addressed

4 experts are featured in this series.

EP. 9 MSKCC Experiences: Successful CAR T Collaborations With Community and International Providers

4 experts are featured in this series.

EP. 10 CAR-T Clinical Trials: Potentially Moving CAR T Into Earlier Lines of MM Treatment

4 experts are featured in this series.

EP. 11 Applying Evidence to Clinical Practice: 63-Year-Old Patient With R/R MM Post Dara-VRd Induction Scenario

4 experts are featured in this series.

EP. 12 CAR T in R/R MM: Key Takeaways and Pearls

Video content above is prompted by the following:

Which patients do you think about for chimeric antigen receptor T-cell therapy (CAR T) in second-line treatment for relapsed/refractory multiple myeloma (cilta-cel vs ide-cel)?
Dr Usmani to ask Dr Mailankody: Can you describe the specific criteria/institutional guidelines used to determine patient eligibility for CAR T referral?
How do nonmedical factors (location, money, etc) impact patient selection?

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