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Opinion|Videos|December 20, 2024

Highlighted Data Review of CAR-T in Early R/R MM

Author(s)Saad Z. Usmani, MD, MBA, FACP, Carlyn Rose Tan, MD , Sham Mailankody, MBBS

Panelists discuss how early-line chimeric antigen receptor T-cell therapy studies, including recent data from trials of cilta-cel (Popat et al) and ide-cel (Ailawadhi et al), are showing promising results in patients with relapsed/refractory multiple myeloma, suggesting potential benefits of moving these treatments into earlier therapeutic settings.

Episodes in this series

4 experts are featured in this series.

EP. 1 Highlighted Data Review of CAR-T in Early R/R MM

4 experts are featured in this series.

EP. 2 Expert Insights: Distinguishing between CARTITUDE-4 vs. KarMMa-3 Trials

4 experts are featured in this series.

EP. 3 CAR-T in R/R MM: Patient Selection & Treatment Sequencing

4 experts are featured in this series.

EP. 4 CAR-T in Earlier Lines of MM Treatment: Patient Eligibility - Considerations between Ide-cel vs. Cilta-cel

4 experts are featured in this series.

EP. 5 MSKCC Insights: CAR T Referral Process

4 experts are featured in this series.

EP. 6 Overview of the CAR T-Cell Therapy Process: Apheresis, Manufacturing, Potential Bridging Therapies, Lymphodepletion, and Infusion

4 experts are featured in this series.

EP. 7 Collaboration With Community Colleagues: Comanagement and Transitions of Care

4 experts are featured in this series.

EP. 8 CAR T Referral Process: Challenges Seen and How They Can Be Addressed

4 experts are featured in this series.

EP. 9 MSKCC Experiences: Successful CAR T Collaborations With Community and International Providers

4 experts are featured in this series.

EP. 10 CAR-T Clinical Trials: Potentially Moving CAR T Into Earlier Lines of MM Treatment

4 experts are featured in this series.

EP. 11 Applying Evidence to Clinical Practice: 63-Year-Old Patient With R/R MM Post Dara-VRd Induction Scenario

4 experts are featured in this series.

EP. 12 CAR T in R/R MM: Key Takeaways and Pearls

Video content above is prompted by the following:

Let’s talk about the data surrounding the use of chimeric antigen receptor T-cell therapy in earlier lines of treatment for relapsed/refractory multiple myeloma:
Cilta-cel
Ide-cel
What are your thoughts on these data?

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