|Articles|January 1, 2003

Oncology NEWS International Vol 12 No 1
Volume 12
Issue 1

Phase II Trial of Phenoxodiol in Recurrent Ovarian Cancer Is launched

WASHINGTON-Marshall Edwards, Inc. has launched a multi-center phase II clinical trial of its anticancer drug phenoxodiol in women with recurrent ovarian and fallopian tube cancers who have failed other forms of chemotherapy.

WASHINGTONMarshall Edwards, Inc. has launched a multi-center phase II clinical trial of its anticancer drug phenoxodiol in women with recurrent ovarian and fallopian tube cancers who have failed other forms of chemotherapy.

A damaged cell normally shuts off production of the antiapoptotic proteins FLIP and XIAP to allow activation of the apoptosis-triggering receptors (Fas, TNFR1, DR3, TRAIL). Cancer cells resist this process by producing large amounts of blocking proteins such as FLIP. Phenoxodiol blocks FLIP and XIAP in cancer cells without harming noncancer cells, the company said in a news release.

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First NCI Health Disparity Grants

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Lumpectomy/Mastectomy Equivalent in Early Breast Cancer

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New Agent Tested in Refractory and Relapsed Ovarian Cancer

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Phase II Trial of Phenoxodiol in Recurrent Ovarian Cancer Is launched

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