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|Videos|September 21, 2022

The GMMG HD7 Trial of Isa-VRd vs VRd in Transplant-Eligible NDMM

Author(s)Ajay K. Nooka, MD, Matthew James Pianko, MD

An expert reviews data from the ongoing GMMG HD7 (German) trial investigating isatuximab in combination with bortezomib, lenalidomide and dexamethasone (Isa-VRd) versus VRd in the treatment of transplant-eligible newly diagnosed multiple myeloma.

Episodes in this series

EP. 1 Frontline Treatment Options for Transplant-Ineligible Newly Diagnosed Multiple Myeloma

EP. 1 Frontline Treatment Options for Transplant-Ineligible Newly Diagnosed Multiple Myeloma

EP. 2 Comparison of Results from the MAIA and SWOG0777 Studies

EP. 2 Comparison of Results from the MAIA and SWOG0777 Studies

EP. 3 Triplet vs Doublet Induction Therapy for Transplant-Ineligible MM and Role of Real-World Evidence

EP. 3 Triplet vs Doublet Induction Therapy for Transplant-Ineligible MM and Role of Real-World Evidence

EP. 4 Treatment Decision-Making Based on Real-World Data in Transplant-Ineligible NDMM

EP. 4 Treatment Decision-Making Based on Real-World Data in Transplant-Ineligible NDMM

EP. 5 Maintenance Therapy in Transplant-Ineligible Multiple Myeloma

EP. 5 Maintenance Therapy in Transplant-Ineligible Multiple Myeloma

EP. 6 Determining Treatment Duration for Transplant-Ineligible Multiple Myeloma

EP. 6 Determining Treatment Duration for Transplant-Ineligible Multiple Myeloma

EP. 7 Unmet Needs of Transplant-Ineligible Multiple Myeloma

EP. 7 Unmet Needs of Transplant-Ineligible Multiple Myeloma

EP. 8 Racial Disparities in the Treatment of Multiple Myeloma Patients

EP. 8 Racial Disparities in the Treatment of Multiple Myeloma Patients

EP. 9 Comparing Combination Treatment Regimens in Transplant-Eligible NDMM

EP. 9 Comparing Combination Treatment Regimens in Transplant-Eligible NDMM

EP. 10 Is There a Role for MRD-Response Adapted Therapy in Transplant-Eligible NDMM?

EP. 10 Is There a Role for MRD-Response Adapted Therapy in Transplant-Eligible NDMM?

EP. 11 The GMMG HD7 Trial of Isa-VRd vs VRd in Transplant-Eligible NDMM

EP. 11 The GMMG HD7 Trial of Isa-VRd vs VRd in Transplant-Eligible NDMM

EP. 12 Treatment Decision-Making Based on Clinical Trial Data in Transplant-Eligible NDMM

EP. 12 Treatment Decision-Making Based on Clinical Trial Data in Transplant-Eligible NDMM

EP. 13 Treatment Decision-Making Based on Real-World Data in Transplant-Eligible NDMM

EP. 13 Treatment Decision-Making Based on Real-World Data in Transplant-Eligible NDMM

EP. 14 Measuring Treatment Response in Transplant-Eligible NDMM after Induction Therapy

EP. 14 Measuring Treatment Response in Transplant-Eligible NDMM after Induction Therapy

Recap: Recent Advances in Multiple Myeloma: Applying Real-world Evidence to Clinical Practice

EP. 15 Recap: Recent Advances in Multiple Myeloma: Applying Real-world Evidence to Clinical Practice

EP. 16 Determining Treatment Duration for Transplant-Eligible NDMM

EP. 16 Determining Treatment Duration for Transplant-Eligible NDMM

EP. 17 Racial Disparities in Presentation, Diagnosis, and Treatment of MM

EP. 17 Racial Disparities in Presentation, Diagnosis, and Treatment of MM

EP. 18 Unmet Needs and Future Perspectives in Transplant-Eligible NDMM

EP. 18 Unmet Needs and Future Perspectives in Transplant-Eligible NDMM

EP. 19 Characterization and Management of High-Risk Patients with MM

EP. 19 Characterization and Management of High-Risk Patients with MM

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Eileen M. O’Reilly, MD; E. Gabriela Chiorean, MD, FASCO; Michael J. Pishvaian, MD, PhD; Brian Wolpin, MD, MPH

PER Tumor Board®: Applying Recent Advances to Transform the Treatment Paradigm in SCLC—Expert Perspectives on New Approvals and Emerging Strategies

PER Tumor Board®: Applying Recent Advances to Transform the Treatment Paradigm in SCLC—Expert Perspectives on New Approvals and Emerging Strategies

Jonathan W. Goldman, MD; Percy Lee, MD, FASTRO; Erminia Massarelli, MD, PhD, MS; Misty D. Shields, MD, PhD

Medical Crossfire®: Integrating Next-Generation Endocrine Targeting Therapies to Improve Outcomes for Patients With HR+/HER2- Breast Cancer

Medical Crossfire®: Integrating Next-Generation Endocrine Targeting Therapies to Improve Outcomes for Patients With HR+/HER2- Breast Cancer

William J. Gradishar, MD, FASCO, FACP; Laura Huppert, MD; Yuan Yuan, MD, PhD

Medical Crossfire®: Improving Patient Outcomes in Myeloproliferative Neoplasms With Novel Therapeutic Approaches

Medical Crossfire®: Improving Patient Outcomes in Myeloproliferative Neoplasms With Novel Therapeutic Approaches

Rami Komrokji, MD; Gabriela Hobbs, MD; John Mascarenhas, MD; Naveen Pemmaraju, MD

$Cases and Conversations™: Sorting Through the Expanding Treatment Options for Patients with Relapsed/Refractory Multiple Myeloma$

Cases and Conversations™: Sorting Through the Expanding Treatment Options for Patients with Relapsed/Refractory Multiple Myeloma

C. Ola Landgren, MD, PhD; Mohamad Mohty, MD, PhD; Surbhi Sidana, MD

Medical Crossfire®: Precision Medicine in Glioma Treatment — Integration of Molecular Profiling to Inform Targeted Therapies

Medical Crossfire®: Precision Medicine in Glioma Treatment — Integration of Molecular Profiling to Inform Targeted Therapies

Vinay K. Puduvalli, MD; Manmeet Ahluwalia, MD, MBA; Stephen J. Bagley, MD, MSCE; Angela Waanders, MD, MPH, MS

Cases & Conversations™: Transforming AML Care—Precision Strategies, Evolving Therapies, and Clinical Insights

Cases & Conversations™: Transforming AML Care—Precision Strategies, Evolving Therapies, and Clinical Insights

Gail J. Roboz, MD; Hagop Kantarjian, MD; Catherine Lai, MD, MPH; Amer Zeidan, MBBS, MHS

Tumor Board: Expert Insights on Managing Classical 𝘌𝘎𝘍𝘙 Mutations, 𝘌𝘎𝘍𝘙 Exon 20 Insertions, and Atypical 𝘌𝘎𝘍𝘙 Mutations in Metastatic NSCLC

Tumor Board: Expert Insights on Managing Classical 𝘌𝘎𝘍𝘙 Mutations, 𝘌𝘎𝘍𝘙 Exon 20 Insertions, and Atypical 𝘌𝘎𝘍𝘙 Mutations in Metastatic NSCLC

Balazs Halmos, MD, MS; Enriqueta Felip, MD, PhD; Julia Rotow, MD

Breaking Down the Rationale for Targeting TROP2 in TNBC

Breaking Down the Rationale for Targeting TROP2 in TNBC

Filipa Lynce, MD; Rita Nanda, MD

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Virginia Kaklamani, MD, DSc; Filipa Lynce, MD; Rita Nanda, MD; Tiffany A. Traina, MD, FASCO

Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Erminia Massarelli, MD, PhD, MS; Misty D. Shields, MD, PhD

Navigating the Adverse Event Landscape in HER2+ GEA Therapy

Navigating the Adverse Event Landscape in HER2+ GEA Therapy

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Geoffery Ku, MD; Shruti Patel, MD

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Jason Hafron, MD; Aaron D. Berger, MD; Arpeet Shah, MD

Cross-Disease Integration of Immunotherapy Innovations

Cross-Disease Integration of Immunotherapy Innovations

Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

Community Practice Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy–Strategies for the Multidisciplinary Team

Community Practice Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy–Strategies for the Multidisciplinary Team

Yana G. Najjar, MD; Sapna Patel, MD

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