
- ONCOLOGY Vol 40, Issue 2
- Volume 40
- Issue 02
- Pages: 137
When the World Stopped: A Lesson in Strength and Second Chances
Yan Leyfman, MD, reflected on resilience and hope in the face of cancer, recounting a 37-year-old diagnosed with stage IV colorectal cancer followed by HIV.
She was only 37 years old—vibrant, ambitious, full of life. When she first walked into the clinic, she carried herself with the quiet resilience of someone used to holding her world together. A 5-ft, 2-in frame, an easy smile that tried to hide exhaustion, and eyes that spoke of sleepless nights spent wondering why her body no longer felt like her own. She had lost weight, she said—about 15 lb—but she brushed it off, insisting she had been eating better, taking care of herself. What worried her most was the blood in her stool, something she’d tried to ignore until she couldn’t anymore.
The workup began like any other. But when the scans came back, the air shifted. There it was—a mass, unmistakable and unrelenting. Stage IV colorectal cancer. Multiple sites involved. She came back to the clinic expecting reassurance, not reality. When we told her the diagnosis, time seemed to splinter. She froze, her eyes widening as the words landed. Then the tears came—raw, uncontrollable. Between sobs, she spoke of dreams now shadowed: a new relationship, fears that her partner might walk away, the uncertainty of keeping her job, and the ache of wondering whether she’d ever be a mother. “I’m all my parents have,” she whispered, trembling. “How am I supposed to tell them?”
There is a silence that follows such moments—a sacred, unbearable quiet. We sat with her, handed her a tissue, and tried to offer what words could not. We discussed next steps: genetic testing, treatment planning, hope threaded through science. She left that day fragile but determined, her parting words echoing, “I’ll be ready next week.”
And she was. When she returned, something had changed. The tears were still there, but behind them glimmered resolve. She smiled faintly. “I’m ready to fight this,” she said. “I’m ready to win.” Yet fate had one more blow to deliver. One of the required pretreatment tests had returned: HIV positive.
My attending and I sat with the result in stunned silence. I remember looking at her chart, her photo on the screen, and feeling my heart tighten. How could one person bear so much? Still, we owed her truth—and compassion. When we told her, the room seemed to vanish around us. She went utterly still. Then the quiet gave way to sobs that seemed to come from somewhere deeper than grief—an eruption of disbelief and loss. “How could this happen? My whole world is falling apart,” she cried.
There are moments in medicine that test the soul more than the science. You learn that healing isn’t only in the chemo, the scans, or the data—it’s in presence. We waited outside for a few minutes, listening to her gather herself. Then we knocked, gently. She wiped her tears, her voice steadier now, her eyes fierce. “This is not going to kill me,” she said. “I’m going to beat this.”
In that moment, she wasn’t just a patient—she was a force of will. The kind of strength that humbles you, reminds you why you chose this path in the first place.
As an oncologist, you are more than a clinician—you are a witness to the human spirit at its rawest. You learn that courage isn’t the absence of fear, but the decision to fight despite it. Her story brought me back to my own. Years ago, as a child of Chernobyl, I too knew what it felt like to be written off by medicine. I remember hearing the whispers of palliative care, feeling the quiet resignation in the room when hope seemed gone. But someone believed in me. A team refused to give up. They saw possibility when all I could see was darkness—and because of them, I’m here.
That is why I chose oncology. Because sometimes, the most powerful prescription we can offer is not a drug, but a belief—in resilience, in redemption, in life itself. Her story is not mine, yet in her courage, I found my reflection.
From the ashes of diagnosis, hope still rises. Always.
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