Moshe Ornstein, MD, MA

Brian Rini, MD, reviews data from the 5-year analysis of the KEYNOTE-426 trial in advanced clear cell renal cell carcinoma.

Robert Motzer, MD, presents the overall survival analysis data from the 4-year follow-up of the CLEAR study in patients with advanced renal cell carcinoma.

The panel wraps up their discussion with a review of how they would approach treating frontline non-clear cell RCC.

The panel shares how they would treat a patient with advanced RCC after disease progression on adjuvant pembrolizumab.

Tian Zhang, MD, explains whether recent data from ESMO 2022 has changed their approach to adjuvant immune therapy in advanced RCC.

The panel continues their discussion of investigational triplet therapies in frontline RCC treatment.

The doctors review data from the COSMIC-313 trial investigating a frontline triplet therapy for advanced RCC.

Best approaches to dosing and dose-reduction of TKI agents in the treatment of advanced RCC.

The panel discusses which patients they would consider switching between immunotherapy combination treatments.

Experts summarize their most common frontline treatment approaches to advanced RCC.

Moshe Ornstein, MD, explains which patients with RCC he observes for progression prior to systemic therapy.

The panel discusses the potential impact of updated data from the CLEAR trial on the treatment of patients with advanced RCC in clinical practice.

Hans Hammers, MD, shares whether the updated CLEAR trial data would make him consider an IO-TKI regimen for patients with advanced RCC over an IO-IO regimen.

Brian Rini, MD, presents updated data from the CLEAR trial of lenvatinib plus pembrolizumab versus sunitinib in frontline advanced renal cell carcinoma.

Experts Ulka N. Vaishampayan, MBBS, and Moshe Ornstein, MD, look toward the future treatment paradigm of both clear cell and non–clear cell renal cell carcinoma.

Before closing out their discussion on renal cell carcinoma, key opinion leaders highlight efforts to optimize the management of non–clear cell disease with immunotherapy.

Contextualizing discussion with clinical trial data and real-world experience, expert hematologist-oncologists consider the role of adjuvant therapy in managing advanced RCC.

Shared insight from Ulka N. Vaishampayan, MBBS, and Moshe Ornstein, MD, on unmet needs in the setting of clear cell and non–clear cell renal cell carcinoma.

Key opinion leaders reflect on novel treatment modalities still under investigation for the management of advanced renal cell carcinoma.

Expert hematologist-oncologists share comprehensive perspective on an array of first-line clinical trials in the setting of advanced renal cell carcinoma.

A brief review of common adverse events inherent in the first-line management of advanced renal cell carcinoma and practical advice on how to mitigate treatment toxicity.

Opening their discussion on the advanced renal cell carcinoma treatment landscape, experts Ulka N. Vaishampayan, MBBS, and Moshe Ornstein, MD, identify cornerstone first-line regimens.

Brian Rini, MD, summarizes the thoughts of his colleagues on the use of lenvatinib plus pembrolizumab to treat advanced renal cell carcinoma.

A panel of oncologists look at what’s in the pipeline for advanced renal cell carcinoma, including trials and treatment options.

Two kidney cancer experts explore the current unmet needs for patients with advanced renal cell carcinoma.

A look at the current unmet needs in front-line renal cell carcinoma treatment.

Oncologists review quality of life data for patients with renal cell carcinoma receiving lenvatinib plus pembrolizumab combination treatments.

Kidney cancer experts explain how they dose lenvatinib in advanced renal cell carcinoma treatment to mitigate toxicities.

An explanation of dosing strategies when treating patients with renal cell carcinoma in the first-line with lenvatinib.

Experts discuss the safety of treating renal cell carcinoma with lenvatinib within different patient risk populations.