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Opinion|Videos|May 23, 2024

Background on Osimertinib Resistance Mechanisms and Unmet Needs Driving Evaluation of Novel Therapies

This segment introduces a discussion on the MARIPOSA-2 trial evaluating amivantamab plus chemotherapy or amivantamab, lazertinib and chemotherapy in EGFR-mutant NSCLC after osimertinib progression.

Episodes in this series

Video 1 - "Background on Osimertinib Resistance Mechanisms and Unmet Needs Driving Evaluation of Novel Therapies"

EP. 1 Background on Osimertinib Resistance Mechanisms and Unmet Needs Driving Evaluation of Novel Therapies

Video 2 - "MARIPOSA-2 Phase 3 Study Design and Treatment Arms"

EP. 2 MARIPOSA-2 Phase 3 Study Design and Treatment Arms

A panel of 3 experts on lung cancer

EP. 3 Patient Demographics and Baseline Disease Characteristics in MARIPOSA-2

A panel of 3 experts on lung cancer

EP. 4 Efficacy Outcomes: Progression-Free Survival, Response Rates, and Duration of Response in MARIPOSA-2

A panel of 3 experts on lung cancer

EP. 5 Safety Profile: Adverse Events and Treatment Modifications in MARIPOSA-2

A panel of 3 experts on lung cancer

EP. 6 Clinical Practice Implications of MARIPOSA-2 Data and Future Directions

A panel of 3 experts on lung cancer

EP. 7 Key Findings and Conclusions from MARIPOSA-2 Trial

EP. 8 Amivantamab/Chemotherapy May Improve Outcomes in Osimertinib- Resistant EGFR-Mutated NSCLC

EP. 8 Amivantamab/Chemotherapy May Improve Outcomes in Osimertinib- Resistant EGFR-Mutated NSCLC

•How frequently does the disease develops resistance to osimertinib in the frontline setting?

•How does amivantamab address the unmet needs of patients who develop resistance to osimertinib?

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