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Opinion|Videos|June 6, 2024

Clinical Practice Implications of MARIPOSA-2 Data and Future Directions

Author(s)Martin Dietrich, MD, PhD, Ticiana Leal, MD, Sandip Patel, MD

This segment summarizes the pivotal efficacy and safety outcomes from the MARIPOSA-2 trial of amivantamab-based regimens in osimertinib-resistant EGFR-mutant NSCLC. It explores the clinical implications of these data and potential future research directions.

Episodes in this series

Video 1 - "Background on Osimertinib Resistance Mechanisms and Unmet Needs Driving Evaluation of Novel Therapies"

EP. 1 Background on Osimertinib Resistance Mechanisms and Unmet Needs Driving Evaluation of Novel Therapies

Video 2 - "MARIPOSA-2 Phase 3 Study Design and Treatment Arms"

EP. 2 MARIPOSA-2 Phase 3 Study Design and Treatment Arms

A panel of 3 experts on lung cancer

EP. 3 Patient Demographics and Baseline Disease Characteristics in MARIPOSA-2

A panel of 3 experts on lung cancer

EP. 4 Efficacy Outcomes: Progression-Free Survival, Response Rates, and Duration of Response in MARIPOSA-2

A panel of 3 experts on lung cancer

EP. 5 Safety Profile: Adverse Events and Treatment Modifications in MARIPOSA-2

A panel of 3 experts on lung cancer

EP. 6 Clinical Practice Implications of MARIPOSA-2 Data and Future Directions

A panel of 3 experts on lung cancer

EP. 7 Key Findings and Conclusions from MARIPOSA-2 Trial

EP. 8 Amivantamab/Chemotherapy May Improve Outcomes in Osimertinib- Resistant EGFR-Mutated NSCLC

EP. 8 Amivantamab/Chemotherapy May Improve Outcomes in Osimertinib- Resistant EGFR-Mutated NSCLC

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Yana G. Najjar, MD; Sapna Patel, MD

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