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Opinion|Videos|May 23, 2024

MARIPOSA-2 Phase 3 Study Design and Treatment Arms

This segment discusses the details of the phase 3 randomized MARIPOSA-2 trial design evaluating amivantamab plus chemotherapy vs amivantamab, lazertinib and chemotherapy vs chemotherapy alone in osimertinib-resistant EGFR-mutant NSCLC.

Episodes in this series

Video 1 - "Background on Osimertinib Resistance Mechanisms and Unmet Needs Driving Evaluation of Novel Therapies"

EP. 1 Background on Osimertinib Resistance Mechanisms and Unmet Needs Driving Evaluation of Novel Therapies

Video 2 - "MARIPOSA-2 Phase 3 Study Design and Treatment Arms"

EP. 2 MARIPOSA-2 Phase 3 Study Design and Treatment Arms

A panel of 3 experts on lung cancer

EP. 3 Patient Demographics and Baseline Disease Characteristics in MARIPOSA-2

A panel of 3 experts on lung cancer

EP. 4 Efficacy Outcomes: Progression-Free Survival, Response Rates, and Duration of Response in MARIPOSA-2

A panel of 3 experts on lung cancer

EP. 5 Safety Profile: Adverse Events and Treatment Modifications in MARIPOSA-2

A panel of 3 experts on lung cancer

EP. 6 Clinical Practice Implications of MARIPOSA-2 Data and Future Directions

A panel of 3 experts on lung cancer

EP. 7 Key Findings and Conclusions from MARIPOSA-2 Trial

EP. 8 Amivantamab/Chemotherapy May Improve Outcomes in Osimertinib- Resistant EGFR-Mutated NSCLC

EP. 8 Amivantamab/Chemotherapy May Improve Outcomes in Osimertinib- Resistant EGFR-Mutated NSCLC

•What are your thoughts regarding the efficacy outcomes observed in MARIPOSA-2?•How did efficacy endpoints compare to the chemotherapy arm?

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