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|Videos|April 18, 2022

Comparison of Older First-Line, Single-Agent Therapies

Author(s)David Aggen, MD, PhD, Robert S. Alter, MD, Arnab Basu, MD, MPH, FACP

Robert Alter, MD compares older, single-agent first line therapies for patients with metastatic clear cell RCC.

Episodes in this series

EP. 1 Trends in RCC Incidence

EP. 1 Trends in RCC Incidence

EP. 2 RCC Histologies

EP. 2 RCC Histologies

EP. 3 Risk Models and Prognostic Factors

EP. 3 Risk Models and Prognostic Factors

EP. 4 Metastatic RCC: Prognosis and Recent Advances in Care

EP. 4 Metastatic RCC: Prognosis and Recent Advances in Care

EP. 5 Biomarker Testing in RCC: Current Approaches

EP. 5 Biomarker Testing in RCC: Current Approaches

EP. 6 Biomarker Testing: Methodologies, Sample Types, and Emerging Data

EP. 6 Biomarker Testing: Methodologies, Sample Types, and Emerging Data

EP. 7 Prognostic Value of Biomarkers in RCC

EP. 7 Prognostic Value of Biomarkers in RCC

EP. 8 The Role of Genetic Mutations in Prognosis and Decision-Making

EP. 8 The Role of Genetic Mutations in Prognosis and Decision-Making

EP. 9 Comparison of Older First-Line, Single-Agent Therapies

EP. 9 Comparison of Older First-Line, Single-Agent Therapies

EP. 10 Newer First-Line Combination Therapy Options

EP. 10 Newer First-Line Combination Therapy Options

EP. 11 Evolution of Combination Therapy As The Standard of Care

EP. 11 Evolution of Combination Therapy As The Standard of Care

EP. 12 Patients Suitable for First-Line, Single-Agent Therapy and NCCN-Recommended Regimens

EP. 12 Patients Suitable for First-Line, Single-Agent Therapy and NCCN-Recommended Regimens

EP. 13 Safety and Efficacy Data: The CheckMate 214 Trial

EP. 13 Safety and Efficacy Data: The CheckMate 214 Trial

EP. 14 Safety and Efficacy Data: The JAVELIN Renal 101 Trial

EP. 14 Safety and Efficacy Data: The JAVELIN Renal 101 Trial

EP. 15 Safety and Efficacy Data: The KEYNOTE-426 Trial

EP. 15 Safety and Efficacy Data: The KEYNOTE-426 Trial

EP. 16 Safety and Efficacy Data: The CheckMate 9ER Trial

EP. 16 Safety and Efficacy Data: The CheckMate 9ER Trial

EP. 17 Safety and Efficacy Data: The CLEAR Trial

EP. 17 Safety and Efficacy Data: The CLEAR Trial

EP. 18 Common Adverse Events with Single-Agent or Combination Therapy

EP. 18 Common Adverse Events with Single-Agent or Combination Therapy

EP. 19 Balancing Treatment Efficacy with Toxicity in Metastatic RCC

EP. 19 Balancing Treatment Efficacy with Toxicity in Metastatic RCC

EP. 20 Strategies for Prevention and Management of Adverse Events

EP. 20 Strategies for Prevention and Management of Adverse Events

EP. 21 Patient-Specific Factors Impacting Treatment Choices in RCC

EP. 21 Patient-Specific Factors Impacting Treatment Choices in RCC

EP. 22 Considerations for Patient-Focused, Shared Decision-Making in RCC

EP. 22 Considerations for Patient-Focused, Shared Decision-Making in RCC

EP. 23 Clinical Pearls on Tailoring Dosing Strategies in Metastatic Kidney Cancer

EP. 23 Clinical Pearls on Tailoring Dosing Strategies in Metastatic Kidney Cancer

EP. 24 The Importance of Team-Based Management and Patient Communication

EP. 24 The Importance of Team-Based Management and Patient Communication

EP. 25 OncView™ Podcast: Safety and Efficacy of Available Treatment Options and Considerations for Patient Management in Metastatic RCC

EP. 25 OncView™ Podcast: Safety and Efficacy of Available Treatment Options and Considerations for Patient Management in Metastatic RCC

EP. 26 Reflections on Novel Targets and Emerging Regimens for RCC

EP. 26 Reflections on Novel Targets and Emerging Regimens for RCC

EP. 27 Clinical Pearls on Recent Advances and the Future of Treatment in RCC

EP. 27 Clinical Pearls on Recent Advances and the Future of Treatment in RCC

EP. 28 Recap: Safety and Efficacy of Available Treatment Options and Considerations for Management of RCC

EP. 28 Recap: Safety and Efficacy of Available Treatment Options and Considerations for Management of RCC

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Virginia Kaklamani, MD, DSc; Tiffany A. Traina, MD, FASCO

Breaking Down the Rationale for Targeting TROP2 in TNBC

Breaking Down the Rationale for Targeting TROP2 in TNBC

Filipa Lynce, MD; Rita Nanda, MD

Breaking Down the Latest Clinical Data for First-line Maintenance and R/R SCLC

Breaking Down the Latest Clinical Data for First-line Maintenance and R/R SCLC

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Hossein Borghaei, DO, MS

Cross-Disease Integration of Immunotherapy Innovations

Cross-Disease Integration of Immunotherapy Innovations

Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

Navigating Treatment Gaps in SCLC: Relapse, Resistance, and Need for New Options

Navigating Treatment Gaps in SCLC: Relapse, Resistance, and Need for New Options

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Giannis Mountzios ΜD, PhD

Radioligand Therapy 101: The Science Behind the Strategy

Radioligand Therapy 101: The Science Behind the Strategy

Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Scott T. Tagawa, MD, MS, FACP, FASCO

Navigating Advances in Neovascular Retinal Disease: Translating Evidence to Practice in AMD, DME, and RVO

Navigating Advances in Neovascular Retinal Disease: Translating Evidence to Practice in AMD, DME, and RVO

SriniVas R. Sadda, MD, FARVO; Mark R. Barakat, MD, FASRS; David A. Eichenbaum, MD, FASRS

Navigating the Adverse Event Landscape in HER2+ GEA Therapy

Navigating the Adverse Event Landscape in HER2+ GEA Therapy

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Geoffery Ku, MD; Shruti Patel, MD

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Virginia Kaklamani, MD, DSc; Filipa Lynce, MD; Rita Nanda, MD; Tiffany A. Traina, MD, FASCO

21st Annual New York Lung Cancers Symposium®

In-Person Event

21st Annual New York Lung Cancers Symposium®

November 14, 2026

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Jason Hafron, MD; Aaron D. Berger, MD; Arpeet Shah, MD

The Rise of Novel HER2-Targeting Therapies in GEA: Mechanisms and Clinical Data

The Rise of Novel HER2-Targeting Therapies in GEA: Mechanisms and Clinical Data

Rahul Gosain, MD, MBA; Rohit Gosain, MD

Revolutionizing TGCT Care with Multidisciplinary Perspectives and Cutting-Edge Targeted Therapies

Revolutionizing TGCT Care with Multidisciplinary Perspectives and Cutting-Edge Targeted Therapies

Mark Agulnik, MD; Lee M. Zuckerman, MD

SimulatEd™: A Roadmap to Personalized Care Plans and Shared Decision-Making in Low-Grade Serous Ovarian Cancer

Case-based Simulation

SimulatEd™: A Roadmap to Personalized Care Plans and Shared Decision-Making in Low-Grade Serous Ovarian Cancer

Rachel N. Grisham, MD

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