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Opinion|Videos|October 29, 2024

ctDNA Insights From INTERCEPT, BESPOKE, COSMOS-CRC-01, and GALAXY Studies

Author(s)Michael J. Pishvaian, MD, PhD, Stacey A. Cohen, MD, Mark Lewis, MD

Panelists discuss how insights from the INTERCEPT, BESPOKE, COSMOS-CRC-01, and GALAXY studies are advancing our understanding of circulating tumor DNA’s (ctDNA) utility in colorectal cancer management, from early detection to treatment monitoring.

Episodes in this series

EP. 1 Colorectal Cancer: Rising Prevalence and the Promise of ctDNA

EP. 1 Colorectal Cancer: Rising Prevalence and the Promise of ctDNA

EP. 2 ctDNA in CRC Management: Evolving Approaches for Personalized Care

EP. 2 ctDNA in CRC Management: Evolving Approaches for Personalized Care

EP. 3 MRD Detection in CRC: Guiding Postsurgical Treatment Decisions and Monitoring

EP. 3 MRD Detection in CRC: Guiding Postsurgical Treatment Decisions and Monitoring

EP. 4 MRD Testing in CRC: Optimizing Chemo-Sparing Strategies and Residual Disease Control

EP. 4 MRD Testing in CRC: Optimizing Chemo-Sparing Strategies and Residual Disease Control

EP. 5 DYNAMIC: ctDNA-Guided Therapy on Adjuvant Chemotherapy Decisions in Stage II Colon Cancer

EP. 5 DYNAMIC: ctDNA-Guided Therapy on Adjuvant Chemotherapy Decisions in Stage II Colon Cancer

EP. 6 ctDNA Insights From INTERCEPT, BESPOKE, COSMOS-CRC-01, and GALAXY Studies

EP. 6 ctDNA Insights From INTERCEPT, BESPOKE, COSMOS-CRC-01, and GALAXY Studies

EP. 7 GALAXY Study: ctDNA-Based MRD Monitoring in Resected CRC

EP. 7 GALAXY Study: ctDNA-Based MRD Monitoring in Resected CRC

EP. 8 GALAXY Study Results: ctDNA Status Predicts Outcomes and Treatment Benefit in CRC

EP. 8 GALAXY Study Results: ctDNA Status Predicts Outcomes and Treatment Benefit in CRC

EP. 9 Treatment Strategies in ctDNA-Positive CRC

EP. 9 Treatment Strategies in ctDNA-Positive CRC

EP. 10 GALAXY 24-Month Data from ESMO 2024: MRD Status and ctDNA Clearance Key in CRC

EP. 10 GALAXY 24-Month Data from ESMO 2024: MRD Status and ctDNA Clearance Key in CRC

EP. 11 CLM in GALAXY: MRD Predicts Adjuvant Therapy Benefit and Prognosis

EP. 11 CLM in GALAXY: MRD Predicts Adjuvant Therapy Benefit and Prognosis

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November 14, 2026

Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Erminia Massarelli, MD, PhD, MS; Misty D. Shields, MD, PhD

Navigating Advances in Neovascular Retinal Disease: Translating Evidence to Practice in AMD, DME, and RVO

Navigating Advances in Neovascular Retinal Disease: Translating Evidence to Practice in AMD, DME, and RVO

SriniVas R. Sadda, MD, FARVO; Mark R. Barakat, MD, FASRS; David A. Eichenbaum, MD, FASRS

(Pharmacist Track) Antibody–Drug Conjugates in Oncology: The Essentials of AE Management for Better Patient Outcomes

(Pharmacist Track) Antibody–Drug Conjugates in Oncology: The Essentials of AE Management for Better Patient Outcomes

Michelle L. Taylor, ANP-BC; Emely Alfaro, DNP, RN, CNS, OCN; Paige Griffith, CRNP; Beth Sandy, MSN, CRNP, FAPO

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