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Opinion|Videos|January 13, 2025

Evolving Landscapes: Personalized Approaches in Later-Line HER2+ Treatment

Author(s)VK Gadi, MD, PhD, Ruta Rao, MD, Jane L. Meisel, MD

Panelists discuss how a third-line approach for a 54-year-old patient treated with a tucatinib-based regimen involves careful consideration of prior treatment responses, comorbidities, and the potential benefits of combining tucatinib with capecitabine and trastuzumab to improve outcomes in HER2+ metastatic breast cancer.

Episodes in this series

EP. 1 Overview of Clinical Data and Treatment Selection in Later-Line HER2+ Metastatic Breast Cancer

EP. 1 Overview of Clinical Data and Treatment Selection in Later-Line HER2+ Metastatic Breast Cancer

EP. 2 Managing T-DXd-Related Toxicity and Intolerance in Later-Line HER2+ Breast Cancer

EP. 2 Managing T-DXd-Related Toxicity and Intolerance in Later-Line HER2+ Breast Cancer

EP. 3 Third-Line Approach: 54-Year-Old Patient Treated With Tucatinib-Based Regimen

EP. 3 Third-Line Approach: 54-Year-Old Patient Treated With Tucatinib-Based Regimen

EP. 4 Evolving Landscapes: Personalized Approaches in Later-Line HER2+ Treatment

EP. 4 Evolving Landscapes: Personalized Approaches in Later-Line HER2+ Treatment

EP. 5 Strategic Screening and Management of Brain Metastases in HER2+ Breast Cancer

EP. 5 Strategic Screening and Management of Brain Metastases in HER2+ Breast Cancer

EP. 6 Intracranial Efficacy Data with With Tucatinib and T-DXd in Brain Metastases

EP. 6 Intracranial Efficacy Data with With Tucatinib and T-DXd in Brain Metastases

EP. 7 Clinical Scenario: Tucatinib-Based Regimens in the Management of Brain Metastases in the 2nd-Line Metastatic Setting

EP. 7 Clinical Scenario: Tucatinib-Based Regimens in the Management of Brain Metastases in the 2nd-Line Metastatic Setting

EP. 8 Evolving Frontline Treatment Strategies and Future Directions in HER2+ Breast Cancer

EP. 8 Evolving Frontline Treatment Strategies and Future Directions in HER2+ Breast Cancer

EP. 9 Managing Brain Metastases in Patients with HER2+ Metastatic Breast Cancer

EP. 9 Managing Brain Metastases in Patients with HER2+ Metastatic Breast Cancer

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