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Opinion|Videos|November 26, 2024

Initial Impressions of the CEPHEUS Clinical Trial in Transplant Not-Preferred NDMM

Author(s)Morie A. Gertz, MD, MACP, Mayo Clinic, Ajai Chari, MD

Panelists discuss how the CEPHEUS trial’s demonstration of improved progression-free survival with daratumumab-VRd versus VRd alone in transplant not-preferred NDMM provides compelling evidence for quadruplet therapy in this setting, though considerations of cost, toxicity management, and patient selection remain important factors in implementation.

Episodes in this series

2 experts are featured in this series.

EP. 1 Current Strategies for Frontline Therapy in Transplant-Preferred NDMM

2 experts are featured in this series.

EP. 2 Brief Overview of PERSEUS, IsKia, and CASSIOPEIA Clinical Trials

2 experts are featured in this series.

EP. 3 Deciding Between Quadruplet and Triplet Therapy in Transplant-Preferred NDMM: Key Considerations

2 experts are featured in this series.

EP. 4 Insights of MAIA, BENEFIT, and IMROZ Trials on Frontline Treatment for Transplant Not-Preferred NDMM

2 experts are featured in this series.

EP. 5 Initial Impressions of the CEPHEUS Clinical Trial in Transplant Not-Preferred NDMM

2 experts are featured in this series.

EP. 6 Clinical Experience in CAR-T-Cell Therapy in Early Relapsed MM and Insights From the CARTITUDE-4 Trial

Video content above is prompted by the following:

What are your impressions of the CEPHEUS data that was recently presented?
How might this impact your clinical practice?

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