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Opinion|Videos|February 17, 2025

Locally Advanced HER2+ Breast Cancer

Author(s)Rohit Gosain, MD, Rahul Gosain, MD, Sarah Sammons, MD

Panelists discuss how, locally advanced HER2-positive breast cancer is characterized by overexpression of HER2 proteins with regional spread beyond the primary tumor, involving either extensive lymph node involvement, chest wall, or skin, but without distant metastases. Treatment typically combines targeted HER2 therapy, chemotherapy, and local interventions.

Episodes in this series

EP. 1 Early-Stage HER2+ Breast Cancer Treatment

EP. 1 Early-Stage HER2+ Breast Cancer Treatment

EP. 2 Locally Advanced HER2+ Breast Cancer

EP. 2 Locally Advanced HER2+ Breast Cancer

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EP. 3 Escalating to TDM-1 Treatment Therapy

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EP. 4 Approach to HER2+ Metastatic Disease Treatment

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EP. 5 Navigating Data Free HER2+ Breast Cancer Treatment

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