Opinion|Videos|November 24, 2025
Risk of Infection and IVIG Use
Author(s)C. Ola Landgren, MD, PhD, Noopur Raje, MD
Panelists discuss how infection prevention and selective IVIG use are critical for maintaining safety during NDMM combination therapy.
Advertisement
Episodes in this series
Panelists discuss how infection risk remains a significant concern in newly diagnosed multiple myeloma (NDMM), particularly with immunosuppressive regimens such as daratumumab-based combinations. They share strategies for prevention and management, including vaccination, prophylaxis, and selective use of intravenous immunoglobulin (IVIG), in patients with recurrent infections or hypogammaglobulinemia. They emphasize balancing infection control with therapy intensity, noting that proactive management can sustain treatment continuity and improve outcomes.
Advertisement
Related to this article
Bhanu Prasad Venkatesulu, MBBS, MD, discussed why fewer radiation oncologists offer prostate brachytherapy and the patients for whom he still recommends it.
Chinmay Jani, MD, explains how air pollution and asbestos contribute to lung cancer deaths beyond tobacco.
Claudine Isaacs, MD, and community oncologists weigh ASCENT-03 and ASCENT-04 data, crossover, and toxicity management with sacituzumab govitecan in TNBC.
The FDA assigned an April 9, 2027, target action date to resubmitted applications for rivoceranib plus camrelizumab in unresectable or metastatic hepatocellular carcinoma.
Adam C. Olson, MD, MSc-GH, discussed letting patients choose between modalities with comparably strong evidence, and the data that shaped his approach.
Data from the phase 3 MANGROVE study support the application for zanubrutinib/rituximab in this mantle cell lymphoma population.
Sunnie Kim, MD, discussed perioperative durvalumab plus FLOT, ctDNA-guided de-escalation, irAE monitoring, and biomarkers in gastroesophageal cancer.
Adam C. Olson, MD, MSc-GH, discussed the infrastructure, training, and shared decision-making behind building a prostate HDR brachytherapy program.
Advertisement
Advertisement
Trending on CancerNetwork
1
Setting Up an HDR Brachytherapy Program Amid a National Decline
2
Zamto-Cel Improves EFS vs R-GemOx in Transplant-Ineligible R/R LBCL
3
Biomarker Sequencing, PD-L1 Status, and FLOT Dosing in Gastroesophageal Cancer
4
CD38-Targeted Immuno-PET Helps Detect Active Multiple Myeloma
5