Opinion|Videos|November 24, 2025
Risk of Infection and IVIG Use
Author(s)C. Ola Landgren, MD, PhD, Noopur Raje, MD
Panelists discuss how infection prevention and selective IVIG use are critical for maintaining safety during NDMM combination therapy.
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Episodes in this series
Panelists discuss how infection risk remains a significant concern in newly diagnosed multiple myeloma (NDMM), particularly with immunosuppressive regimens such as daratumumab-based combinations. They share strategies for prevention and management, including vaccination, prophylaxis, and selective use of intravenous immunoglobulin (IVIG), in patients with recurrent infections or hypogammaglobulinemia. They emphasize balancing infection control with therapy intensity, noting that proactive management can sustain treatment continuity and improve outcomes.
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