
Safety Signals of Daratumumab + KRd: Real-World Translation
Panelists discuss how daratumumab plus KRd demonstrates manageable toxicity and strong real-world feasibility with appropriate supportive care.
Episodes in this series

Panelists discuss how safety findings from ADVANCE align with prior daratumumab experience, confirming manageable toxicity profiles when administered with carfilzomib, lenalidomide, and dexamethasone (KRd). They highlight key adverse events—hematologic suppression, infusion reactions, and infection risk—while noting low discontinuation rates. Supportive measures such as antiviral prophylaxis, intravenous immunoglobulin supplementation, and careful monitoring help mitigate risks. They stress that real-world success depends on early recognition and multidisciplinary coordination to manage adverse effects without compromising efficacy.
Newsletter
Stay up to date on recent advances in the multidisciplinary approach to cancer.



















































































