April 18th 2024
The FDA has approved alectinib for the adjuvant treatment of patients with ALK-positive non-small cell lung cancer with tumors that are least 4 cm or node positive, as detected by an FDA-approved test.
Breaking Down Biomarkers in Non–Small Cell Lung Cancer: A Case-Based Discussion for the Oncology Nurse
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Go To PER in Chicago
May 31, 2024 - June 2, 2024
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The Top 10 Oncogenic Drivers in NSCLC for 2023: What You Need to Know on Tumor Testing, Targets, and Treatment Strategies to Move the Field Forward
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Expanding the Armamentarium of Actionable Mutations in NSCLC: Uncovering the Potential of CEACAM5 as a Therapeutic Target
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Pathology Implications for CEACAM5 as a Therapeutic Target in Advanced NSCLC
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Medical Crossfire®: What Are Effective Strategies for Onco-Nurses to Improve Outcomes in Patients with Small Cell Lung Cancer?
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Virtual Show Me the Data™: How HER2, HER3, and TROP2 Targeted Strategies Will Impact Evolving Paradigms in NSCLC
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42nd Annual CFS®: Innovative Cancer Therapy for Tomorrow®
November 13-15, 2024
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Community Practice Connections™: 5th Annual Precision Medicine Symposium – An Illustrated Tumor Board
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How CEACAM5 Expression Can Be Measured and Leveraged in NSCLC Care: Current Developments & Future Therapeutic Opportunities
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Medical Crossfire®: Where Are We in the World of ADCs? From HER2 to CEACAM5, TROP2, HER3, CDH6, B7H3, c-MET and Beyond!
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Community Oncology Connections™: Overcoming Barriers to Testing, Trial Access, and Equitable Care in Cancer
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22nd Annual Winter Lung Cancer Conference®
January 31, 2025 - February 2, 2025
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Dialogues With the Surgeon on Integration of Systemic Therapies in Perioperative Settings for NSCLC: Looking at EGFR, ALK, IO, and Beyond…
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‘Unprecedented’ Survival Times Result From Adding Docetaxel to Treatment Regimen for NSCLC
July 1st 2000DAVIS, Calif-“Unprecedented” survival times for patients with stage IIIB non–small-cell lung cancer (NSCLC) have resulted from adding taxane sequencing to combined-modality therapy with radiotherapy plus cisplatin (Platinol) and etoposide. These results from the Southwestern Oncology Group (SWOG) 9504 trial were presented at the ASCO meeting by David R. Gandara, MD, of the University of California Cancer Center, Davis.
Study Confirms Efficacy of Concurrent Radiotherapy and Paclitaxel for NSCLC
July 1st 2000BOSTON-A regimen of concurrent radiation and weekly administration of paclitaxel (Taxol)/carboplatin (Paraplatin), the most commonly used treatment for nonresectable non–small-cell lung cancer (NSCLC), was evaluated in a national cooperative group trial and shown to be effective.
Antibody to VEGF Plus Carboplatin/Paclitaxel Improves Outcomes in Previously Untreated NSCLC
July 1st 2000KNOXVILLE, Tennessee-An experimental protocol that adds an anti-VEGF agent to carboplatin (Paraplatin)/paclitaxel (Taxol) chemotherapy may improve outcomes more than chemotherapy alone in patients with previously untreated advanced non–small-cell lung cancer (NSCLC).
Tobacco Use in the United States, 1900–1999
July 1st 2000Smoking-once a socially accepted behavior-is the leading preventable cause of death and disability in the United States. During the first decades of the 20th century, lung cancer was rare; however, as cigarette smoking became increasingly popular,
Paclitaxel/Carboplatin and Radiation May Double Survival in NSCLC Patients
July 1st 2000CHAPEL HILL, NC-In the treatment of non–small-cell lung cancer (NSCLC), combination chemotherapy with paclitaxel (Taxol) and carboplatin (Paraplatin) given before and during radiation therapy may double survival time over that seen with radiation alone.
Survival Advantage Seen for Neoadjuvant Docetaxel in Stage III NSCLC, but Study Stirs Criticism
July 1st 2000HELSINKI, Finland-A large phase III international study has shown a survival advantage for neoadjuvant chemotherapy with single-agent docetaxel (Taxotere) in selected patients with stage III non–small-cell lung cancer (NSCLC). The analysis of the study, presented at the ASCO meeting, was, however, met with criticism from investigators outside the study.
Combination Chemoradiotherapy With Gemcitabine: Potential Applications
July 1st 2000Gemcitabine (Gemzar) is a novel deoxycitidine drug that has demonstrated promising single-agent activity in non–small-cell lung cancer and has been proven to be a potent radiosensitizer. Although the exact mechanism of the
Advances in Treatment of Inoperable NSCLC: Gemcitabine Doublets-A Promising Alternative
July 1st 2000Gemcitabine (Gemzar) was originally approved for use in combination with cisplatin (Platinol) for the treatment of advanced non–small-cell lung cancer (NSCLC). Research began to focus on combining gemcitabine with newer
Gemcitabine/Cisplatin as Induction Therapy for Stage IIIA N2 Non–Small-Cell Lung Cancer
July 1st 2000Because the majority of patients with stage IIIA N2 non–small-cell lung cancer (NSCLC) ultimately die of distant metastases, recent efforts to improve their intermediate- and long-term survival have focused on neoadjuvant
Gemcitabine/Alimta in Locally Advanced or Metastatic Non–Small-Cell Lung Cancer
July 1st 2000The search for new combination chemotherapeutic regimens for the treatment of non–small-cell lung cancer is motivated not only by the desire to increase the objective tumor response and survival rates, but also by the desire
Paclitaxel/Carboplatin vs Paclitaxel/Gemcitabine in Advanced Non–Small-Cell Lung Cancer
July 1st 2000The Hellenic Cooperative Oncology Group conducted a randomized phase III trial to compare paclitaxel (Taxol) 200 mg/m² IV 3-hour infusion on day 1 plus carboplatin (Paraplatin) at an area under the curve (AUC) of 6 (group
Triple- vs Double-Agent Chemotherapy for Advanced Non–Small-Cell Lung Cancer
July 1st 2000In our previous phase I/II studies, both the cisplatin (Platinol), gemcitabine (Gemzar), and vinorelbine (Navelbine) (PGV), and cisplatin, gemcitabine, and paclitaxel (Taxol) (PGT) regimens produced a median survival of
Gemcitabine, Paclitaxel, and Carboplatin for Advanced Non–Small-Cell Lung Cancer
July 1st 2000The purpose of this study was to evaluate the combination of gemcitabine (Gemzar), paclitaxel (Taxol), and carboplatin (Paraplatin) in patients with advanced non–small-cell lung cancer (NSCLC). Previously untreated
Study Finds Estrogen May Fuel Lung Cancer Growth
June 1st 2000Long known to be instrumental in fueling the growth of breast cancer, estrogen may spur the same process in lung cancer, according to the findings of a University of Pittsburgh study presented at the annual meeting of the American Association for
Newer Chemotherapy Regimens Boost Survival in NSCLC
June 1st 2000ASCO-Treatment with chemotherapy extends the lives of patients with advanced lung cancer and should become a standard treatment option offered to these patients, according to two papers presented at the 36th Annual Meeting of the American Society of Clinical Oncology (New Orleans).
Home Counseling Program for Women With Lung Cancer to Be Studied
May 1st 2000Researchers at Memorial Sloan Kettering Cancer Center are examining the effectiveness of bringing psychological support into the homes of women with advanced stages of lung cancer through telephone and videophone counseling programs
German Screening Program Detects Early Lung Cancer
May 1st 2000NEW YORK-Resection with intent to cure was possible for all but one of the lung cancers identified in a German screening program using low-dose spiral CT scans. Of the 13 cancers identified, eight were stage I, Stefan Diederich, MD, a staff radiologist at the University of Münster, said at the Second International Conference on Screening for Lung Cancer. The inoperable lesion was stage IIIB. However, it was resected after preoperative chemotherapy. One lesion was small-cell cancer, six were adenocarcinomas, and six were squamous cell carcinomas.
Group Arrives at Consensus on Lung Cancer Screening Research
May 1st 2000NEW YORK-As the Early Lung Cancer Action Project (ELCAP) continues to focus on lung cancer screening and diagnosis, a consensus has been reached on a number of points affecting the future of the research and variants of its single-arm design.
New Spiral CT Techniques May Cut Cost, Refine Capabilities
May 1st 2000NEW YORK-The main challenges in the continuing development of low-dose spiral CT screening for lung cancer are “cost, flow, and efficiency,” Stanley H. Fox, PhD, General Electric Med Systems, Milwaukee, said at the Second International Conference on Screening for Lung Cancer.
Studies Project Cost Effectiveness of Lung Cancer Screening
May 1st 2000NEW YORK-The cost effectiveness of screening high-risk populations for lung cancer with spiral low-dose CT scans appears to be reasonable, according to two researchers who used somewhat different statistical models and data to arrive at this conclusion. Both researchers presented their results at the Second International Conference on Screening for Lung Cancer.
Low-Dose CT Screening Detects NSCLC: ELCAP Update
March 1st 2000Although the incidence of non-small-cell lung cancer (NSCLC) is similar to that of other types of cancer, the death rate tends to be higher because lung cancer often is not detected until it is the size of an orange. “There is no reason why
Photodynamic Therapy in Lung Cancer
March 1st 2000As a practicing physician, Dr.Ost’s perspective on the use of photodynamic therapy (PDT) in the treatment of lung cancer is informative and helpful, particularly regarding its application in the multimodality setting. My comments represent the viewpoint of a scientist involved in the clinical use of PDT in an academic tertiary referral institution.