April 18th 2024
The FDA has approved alectinib for the adjuvant treatment of patients with ALK-positive non-small cell lung cancer with tumors that are least 4 cm or node positive, as detected by an FDA-approved test.
Breaking Down Biomarkers in Non–Small Cell Lung Cancer: A Case-Based Discussion for the Oncology Nurse
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Go To PER in Chicago
May 31, 2024 - June 2, 2024
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The Top 10 Oncogenic Drivers in NSCLC for 2023: What You Need to Know on Tumor Testing, Targets, and Treatment Strategies to Move the Field Forward
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Expanding the Armamentarium of Actionable Mutations in NSCLC: Uncovering the Potential of CEACAM5 as a Therapeutic Target
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Pathology Implications for CEACAM5 as a Therapeutic Target in Advanced NSCLC
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Medical Crossfire®: What Are Effective Strategies for Onco-Nurses to Improve Outcomes in Patients with Small Cell Lung Cancer?
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Virtual Show Me the Data™: How HER2, HER3, and TROP2 Targeted Strategies Will Impact Evolving Paradigms in NSCLC
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42nd Annual CFS®: Innovative Cancer Therapy for Tomorrow®
November 13-15, 2024
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Community Practice Connections™: 5th Annual Precision Medicine Symposium – An Illustrated Tumor Board
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How CEACAM5 Expression Can Be Measured and Leveraged in NSCLC Care: Current Developments & Future Therapeutic Opportunities
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Medical Crossfire®: Where Are We in the World of ADCs? From HER2 to CEACAM5, TROP2, HER3, CDH6, B7H3, c-MET and Beyond!
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Community Oncology Connections™: Overcoming Barriers to Testing, Trial Access, and Equitable Care in Cancer
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22nd Annual Winter Lung Cancer Conference®
January 31, 2025 - February 2, 2025
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Dialogues With the Surgeon on Integration of Systemic Therapies in Perioperative Settings for NSCLC: Looking at EGFR, ALK, IO, and Beyond…
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Low-Dose Gemcitabine-RT Combination Promising in NSCLC
April 1st 2001NEW YORK-Median survival has pushed past 18 months in a trial of concurrent low-dose gemcitabine (Gemzar) and radiation therapy in highly selected patients with stage III non-small-cell lung cancer (NSCLC), according to a report at the Chemotherapy Foundation Symposium XVIII.
New NCCN Recommendations for Small-Cell Lung Cancer
April 1st 2001FORT LAUDERDALE, Florida-Modifications in the National Comprehensive Cancer Network’s (NCCN) 2001 guideline for small-cell lung cancer (SCLC) include changes in surgical management of SCLC and carcinoid tumors, as well as treatment modifications involving the timing and dose of chest radiotherapy, use of prophylactic cranial irradiation, and additional drugs available for relapsed patients.
State of the Art of Non-Small-Cell Lung Cancer in the New Millennium
March 3rd 2001Lung cancer is the leading cause of cancer death worldwide, with mortality rates in most developed countries ranging from 35 to 95 fatalities per 100,000 in men and 10 to 20 deaths per 100,000 in women.[1] Non-small-cell lung cancer is the most
Novel Approaches in the Treatment of Non-Small-Cell Lung Cancer
A wealth of data indicates that certain genetic abnormalities can target specific cytotoxic drugs and intervene at an early step as a mechanism of resistance in the treatment of non-small-cell lung cancer. Therefore prescribing
Gemcitabine and Nonplatinum Combinations in Non-Small-Cell Lung Cancer
March 3rd 2001Gemcitabine (Gemzar), paclitaxel (Taxol), docetaxel (Taxotere), and vinorelbine (Navelbine) are among the most active agents for the treatment of non-small-cell lung cancer and are generally more active than platinum
Treatment of Elderly Patients With Non-Small-Cell Lung Cancer
March 3rd 2001One of the main reasons for the increased acceptance of chemotherapy for both early and advanced non-small-cell lung cancer is the clinical availability of several new cytotoxic drugs. These less toxic, yet highly effective, new
Gemcitabine and Cisplatin Combination in Early-Stage Non-Small-Cell Lung Cancer
March 3rd 2001A number of randomized clinical trials now support the conclusion that the combined-modality regimen that includes gemcitabine (Gemzar) and cisplatin (Platinol) may improve survival in disseminated non-small-cell lung
Optimizing Chemoradiation in Locally Advanced Non-Small-Cell Lung Cancer
March 3rd 2001Gemcitabine has demonstrated activity in a broad range of solid tumors with good tolerance. In combined modality therapy, gemcitabine has achieved response rates ranging between 30% and 60% in patients with non-small-cell
Bexarotene May Extend Survival in Lung Cancer Patients
March 1st 2001At a recent meeting of the National Cancer Institute, the European Organization for Research and Treatment of Cancer, and the American Association for Cancer Research in Amsterdam, results from a phase I/II clinical trial were presented that
Relieving Symptoms of Lung Cancer and Its Treatment
March 1st 2001NEW YORK-Shortness of breath, pain, and fatigue are among the most common symptoms in patients with advanced lung cancer. An oncology nurse whose practice is exclusively patients with thoracic malignancies discussed the management of symptoms and side effects of lung cancer and the importance of assessment in this setting at a Cancer Care, Inc. teleconference for health care professionals.
Brachytherapy for Carcinoma of the Lung
March 1st 2001An estimated 157,000 patients died of lung cancer in the United States in the year 2000.[1] Although surgery can be curative, only about 20% of patients are amenable to complete surgical resection. Most of the other patients are treated with radiation
Synthetic Anthracycline Produces High Response Rates in SCLC
February 1st 2001TOKYO, Japan-Amrubicin (SM-5887), a completely synthetic anthra-cycline, is "highly active" and well tolerated in small-cell lung cancer (SCLC), Shunichi Negoro, MD, of the Department of Pulmonary Medicine, Osaka City General Hospital, Japan, said at the 9th World Conference on Lung Cancer.
Declines in Lung Cancer Rates-California, 1988-1997
February 1st 2001Cigarette smoking is the leading cause of lung and bronchus cancer. During 1988-1997, per capita cigarette smoking in California declined more than twice as rapidly as it did in the rest of the country. To characterize lung cancer incidence in
Topotecan Active as First-Line Combination Therapy for Advanced Non-Small-Cell Lung Cancer
February 1st 2001A new study presented at the Ninth World Congress on Lung Cancer demonstrated that topotecan (Hycamtin) in combination with carboplatin (Paraplatin) is active as a first-line treatment of advanced non-small-cell lung cancer. Topotecan
Few Long-Term SCLC Survivors With Current Rx
February 1st 2001CHICAGO-Although concomitant platinum-based systemic chemotherapy and thoracic radiotherapy have yielded the best short-term survival rates for patients with limited-stage small-cell lung cancer (SCLC), this approach produces few long-term survivors because local failure and distant metastasis are common.
Combination of Docetaxel and Gemcitabine Effective in Non-Small-Cell Lung Cancer
February 1st 2001The combination of docetaxel (Taxotere) and gemcitabine (Gemzar) is active as first-line therapy for advanced, metastatic non-small-cell lung cancer and appears to be generally well tolerated, according to the results of a phase II study published in
Lessons Learned From Large Lung Cancer Screening Program
January 1st 2001NEW YORK-A program to screen for lung cancer that was remarkably successful in recruiting participants has produced some surprises and taught the investigators some lessons about what to expect from large-scale lung cancer screening.
Book Review: Lung Cancer Therapy Annual 2000
January 1st 2001In an era of information "overload" for the practicing oncologist, keeping up with the latest therapies for the many distinct clinical scenarios that arise in daily practice can be quite a challenge. Thus, a concise synthesis of the current knowledge in a field, such as provided in Lung Cancer Therapy Annual 2000 by Drs. Heine Hansen and Paul Bunn, can be quite useful. These authors, whose clinical expertise and contributions to lung cancer therapy are internationally acknowledged, offer a complete review of the literature pertaining to lung cancer therapy from the year 1999, including a review of abstracts from major meetings. A brief summary is provided at the end, outlining standard, accepted strategies based on histologic and stage-by-stage criteria. This text serves as a reference that summarizes the major existing literature, evaluates the strength of the evidence, and makes reasonable recommendations on how to proceed with clinical care.
British Trials Assessing Value of Chemo in Advanced NSCLC
January 1st 2001TOKYO, Japan-Large, multicenter trials underway in the United Kingdom are questioning whether chemotherapy is actually worth it for patients with advanced non-small-cell lung cancer (NSCLC), according to Jeremy Steele, MD, of the Division of Hematology, Oncology and Imaging, St. Bartholomew’s Hospital, London.
Lung Cancer Vaccine Demonstrates Enhanced Antitumor Immunity
January 1st 2001Ravi Salgia, MD, PhD, and colleagues at Dana-Farber Cancer Center presented an encouraging follow-up report on an initial clinical trial of Cell Genesys’ GVAX lung cancer vaccine at the Ninth World Conference on Lung Cancer in Tokyo,
Sputum Cytology Complements CT in Lung Cancer Screening Effort
January 1st 2001NEW YORK-The development of computers and diagnostic platforms is facilitating mass screening for lung cancer not only with helical CT but also with sputum cytology, according to Melvyn S. Tockman, MD, PhD, professor of medicine and director, Program in Molecular Screening, H. Lee Moffitt Cancer Center & Research Institute, University of South Florida, Tampa.