Oncology Vol 28 No 4_Suppl_1

Permanent prostate brachytherapy (PPB) is a well-established treatment for localized prostate cancer. The future of PPB relies upon the quality training of future residents; however, current training requirements are frequently inadequate. Our objective was to design and implement a unique training program that utilized a phantom-based simulator to teach the process of quality assurance (QA) and improve PPB education.

This prospective study expands upon prior studies to further evaluate SBRT efficacy and QOL for a large patient population that includes low-, intermediate-, and high-risk prostate cancer patients.

To investigate outcomes in intermediate-risk prostate cancer patients receiving dose-escalated external beam radiation therapy (RT) with or without short-course androgen deprivation therapy (ADT).

To determine if there is an influence of sociodemographic factors on biochemical control (bNED) and overall survival (OS) in prostate cancer (CaP).

This study estimates RT doses received by organs of interest during protocol treatment to determine whether the findings might explain these observations.

We hypothesized that the promising outcomes with partial-bladder treatment might be due to the effects of hypofractionation. We thus aimed to analyze the clinical impact of hypofractionation on local control and to characterize the radiation response of a bladder cancer cell line with regard to clonogenic survival.

One clinical observation is that a decrease in tumor enhancement on CT scans after cytotoxic therapy is generally regarded as a good response. We hypothesized that measuring this phenomenon would correlate with local control of human pancreatic adenocarcinoma (PDAC).

Chemoradiation for biliary tract cancers (BTCs) has been associated with substantial toxicities due to the large, irregular target volumes surrounded by critical normal tissues. The purpose of this study was to evaluate patient tolerability and acute toxicity of chemoradiation with intensity-modulated radiation therapy (IMRT) for BTCs.

In this study, we investigate the role of ALDH expression in predicting survival and patterns of disease recurrence in pancreatic adenocarcinoma patients treated with chemoradiation following pancreatectomy.

For patients with pancreatic cancer, we compared direct care costs, patient retention rates, and survival outcomes for patients treated in our institution’s pancreatic multidisciplinary clinics (MDCs) with those evaluated within the institution but outside the MDC.

Evaluation of liver function following high-dose liver stereotactic body radiation therapy (SBRT) in the treatment of metastatic and primary malignancies of the liver utilizing the Child-Pugh score classification system.

Hypofractionated whole-breast irradiation (HF-WBI) following breast-conserving surgery has produced excellent outcomes, but utilization remains limited. We evaluated the impact of a clinical pathway on adoption of HF-WBI in a large integrated radiation oncology network.

An unmet clinical need in breast cancer (BC) management is the identification of which patients will respond to radiation therapy (RT). We hypothesized that the integration of post-RT clonogenic survival data with gene expression data across a large spectrum of BC cell lines would generate a BC-specific RT sensitivity signature predictive for RT response in BC patients and allow identification of patients with tumors refractive to conventional therapy.

Using repeated measures analyses, we analyzed the data from the originally published N06C4 prospective trial and present here the CTCAE-based temporal profile of acute skin toxicities, when time factor was considered.

We aim to examine the difference between outcomes in young women (aged < 40 y) treated with breast-conserving therapy consisting of partial breast surgery and radiation therapy vs mastectomy.

The goal of this study is to use a national database to examine how practice patterns changed prior to versus after publication of the ASTRO accelerated partial breast irradiation guideline.

The goal of this study is to assess locoregional outcomes associated with breast cancer subtype in stage III locally advanced breast cancer patients after surgery, radiation therapy, and modern systemic therapy.

We examined whether presenting stage at time of breast cancer diagnosis has changed over time in Florida and whether there is variation in this change with respect to race, ethnicity, and socioeconomic status.