Setanaxib/Pembrolizumab Improves Survival in Head and Neck Cancer
Phase 2 data also highlight an improvement in disease control rate with setanaxib/pembrolizumab in squamous cell carcinoma of the head and neck.
64 Empowering Medical Students to Deliver Breast Health Education: A Community-Based Initiative
65 Racial Disparities in Treatment Patterns and Outcomes Among HER2-Low Metastatic Breast Cancer Patients Treated in US Community Oncology Practices
FDA Approves Noninvasive Stool RNA Test for Colorectal Cancer Screening
Data from the phase 3 CRC-PREVENT trial support the sensitivity of ColoSense in the detection of colorectal cancer.
Zenocutuzumab Earns FDA Priority Review in NRG1+ NSCLC, Pancreatic Cancer
Data from the phase 1/2 eNRGy trial support the biologics license application for zenocutuzumab in NRG1-positive NSCLC and PDAC.
ctDNA Shows Prognostic Value in Primary Breast Cancer
Findings suggest that patients with breast cancer and consistently negative circulating tumor DNA tests tend to have improved clinical outcomes.
Lasting Responses Observed With TAR-200 in BCG-Unresponsive NMIBC
All patients with a response to TAR-200 did not have progression to muscle-invasive bladder cancer or metastatic disease in the SunRISe-1 trial.
Nivolumab/Ipilimumab Receive Type II Validation by EMA in MSI-H/dMMR mCRC
CheckMate-8HW assessed the efficacy of first-line nivolumab plus ipilimumab in patients with MSI-H/dMMR metastatic colorectal cancer.
HCT Rates Increase Across Ethnic/Racial Subgroups in Multiple Myeloma, Lymphoma
Investigators analyzed data from the Center for International Blood and Marrow Transplant Research who underwent autologous or allogeneic transplants.
FDA Accepts BLA for Subcutaneous Nivolumab in Solid Tumor Indications
Data from the CheckMate-67T trial support the biologics license application for subcutaneous nivolumab in multiple solid tumors.
Administering CAR T-Cell Therapy and Bispecific Agents in Nursing Practice
Registered nurses discuss research related to agents like ciltacabtagene autoleucel presented at the 2024 Oncology Nursing Society Congress.
66 A Comparative Analysis of Changes in Treatment Recommendation for Black and White Patients With Ductal Carcinoma In Situ Using a 7-Gene Predictive Biosignature: Analysis of the PREDICT Study
BCRFS Seen With Apalutamide Combo in Entire High-Risk Prostate Cancer Group
Data from a phase 2 study may support apalutamide plus androgen deprivation in high-risk localized prostate cancer following radical prostatectomy.
67 Disparities in Regional Anesthesia Block Acceptance for Mastectomy With Reconstruction Surgery in a Standardized Setting
Novel Oncolytic Immunotherapy Yields Enduring Responses in High-Risk NMIBC
Treatment with cretostimogene grenadenorepvec appears tolerable among patients with high-risk BCG–unresponsive NMIBC in the phase 3 BOND-003 trial.
18F-PSMA-1007 PET/CT Improves Staging Vs MRI in Prostate Cancer
Findings support the use of 18F-PSMA-1007 PET/CT in the preoperative workflow of intermediate- and high-risk prostate cancer.
HIFU Yields Noninferior Outcomes Vs Prostatectomy in Local Prostate Cancer
Functional consequences appeared to be lower with HIFU compared with radical prostatectomy in a prospective trial.
Acalabrutinib Combo Yields PFS Improvement Vs SOC in Mantle Cell Lymphoma
Data also highlight a favorable overall survival trend with the acalabrutinib regimen in the phase 3 ECHO trial.
Data Highlight Pervasive Racial/Ethnic Disparities in Health Care
Findings from a health disparities report may support new policies designed to narrow persistent racial and ethnic disparities in health outcomes.
Outpatient Bispecific Therapy May Be Feasible and Safe in Cancer
Collaboration among nurses, social workers, and others may help in safely administering outpatient bispecific T-cell engager therapy to patients.
T-DXd Yields Consistent Results in HER2-Overexpressing NSCLC
T-DXd given at 2 dose levels continued to show anti-tumor activity in patients with HER2-overexpressing non–small cell lung cancer.
Pembrolizumab Combo Yields Significant OS in HER2+ Gastric/GEJ Cancer
The primary end point of overall survival was met in the KEYNOTE-811 trial assessing pembrolizumab in HER2-positive gastrointestinal cancer.
68 Magnetic Tracer Increases Surgical Productivity and Reduces Time to Surgery When Compared With Standard Lymph Node Mapping Modalities
Venetoclax Elicits Enduring Responses in R/R Chronic Lymphocytic Leukemia
Phase 3b data support venetoclax as a treatment option in CLL for patients with or without B-cell receptor–associated kinase inhibitor treatment.
Novel Modalities Yield New Era for Surgical Oncology in CRC
Immunotherapy may be an “elegant” method of managing colorectal cancer, says Gregory Charak, MD.
Alectinib “First of Many Approvals” In ALK+ NSCLC
D. Ross Camidge, MD, PhD, spoke about how the approval of alectinib is the beginning of multiple other approvals for patients with ALK-positive NSCLC.
USPSTF Recommends Breast Cancer Screening Starting at Age 40
Biennial screening mammography is recommended for those who are 40 to 74 years old rather than individualizing screening decisions in this age group.
Managing Cranial Nerve Impairment in Multiple Myeloma Following Cilta-cel
Nurses should be educated on cranial nerve impairment that may affect those with multiple myeloma who receive cilta-cel, says Leslie Bennett, MSN, RN.
Glecirasib Shows Promising Efficacy in KRAS G12C+ Advanced NSCLC
Those who have been previously treated for KRAS G12C–mutated advanced NSCLC may benefit from treatment with glecirasib.
Cilta-cel May Offer Another Path in Previously Treated Multiple Myeloma
Treatment with cilta-cel may give patients with multiple myeloma “more time,” according to Ishmael Applewhite, BSN, RN-BC, OCN.