BETA
Your AI-Trained Oncology Knowledge Connection!
Maintenance Pembrolizumab Did Not Improve PFS in Small-Cell Lung Cancer
This video examines a phase II trial that studied maintenance pembrolizumab in extensive-stage small-cell lung cancer.
Frontline Bostunib vs Imatinib in Chronic Myeloid Leukemia
This video highlights results of the BFORE trial, which tested bosutinib vs imatinib in newly diagnosed chronic myeloid leukemia patients.
Endoscopic Therapy in Barrett Esophagus and Early Cancer
This video reviews the use of endoscopic therapy for the management of Barrett esophagus and early esophageal cancer.
Use of SBRT in Treating Pancreatic Cancer
This video highlights the evolution of stereotactic body radiation therapy in the treatment of pancreatic cancer.
Radiation Therapy Options in Small-Cell Lung Cancer
This video reviews options for radiation therapy in the treatment of small-cell lung cancer, including dosing frequency and use of thoracic and cranial irradiation in extensive-stage disease.
Treatment of Low-Lying Early Rectal Cancer
This video examines the treatment of patients with low-lying rectal cancer and explores options such as neoadjuvant chemoradiotherapy, which could improve the efficacy of surgery.
Role of Stereotactic Ablative Radiotherapy in Early-Stage Lung Cancer
This video examines the role of radiation therapy in early-stage lung cancer and some of the data comparing stereotactic ablative radiotherapy vs surgery in these patients.
Treating Locally Advanced Penile Cancer
This video examines the treatment of locally advanced penile cancer and whether an organ-sparing chemoradiotherapy approach might be an option instead of surgery.
Managing Side Effects of Estrogen Deprivation in Breast Cancer Patients
This video examines how to manage the side effects of estrogen deprivation in breast cancer patients, including vaginal dryness and hot flashes.
Late Effects of Estrogen Deprivation in Breast Cancer
This video examines the late effects of estrogen deprivation in both younger and older breast cancer patients, including bone thinning, heart disease, and dementia.
Options in BCG-Refractory Bladder Cancer for Radical Cystectomy–Ineligible Patients
This video examines second-line treatment options for non-muscle invasive bladder cancer patients who relapse after BCG therapy and are not eligible for radical cystectomy.
HIPEC for Colorectal Cancer With Peritoneal Carcinomatosis
This video reviews the use of hyperthermic intraperitoneal chemotherapy with cytoreductive surgery in colorectal cancer with peritoneal carcinomatosis.
Optimizing Radiotherapy With Immunotherapy in Lung Cancer Treatment
This video examines how the use of radiation therapy in patients on immunotherapy can trigger immunogenic cell death, and reviews some of the challenges related to unwanted immune responses from radiotherapy.
Immunotherapies Show Promise in Small-Cell Lung Cancer
This video reviews immunotherapy trials in small-cell lung cancer, including studies on pembrolizumab, nivolumab monotherapy, and nivolumab in combination with ipilimumab.
Should IMRT Be the New Standard in Esophageal Cancer?
This video discusses the use of intensity-modulated radiation therapy and whether it should be the new standard for treating patients with esophageal cancer.
IMRT vs Proton Therapy in Esophageal Cancer
This video reviews the advantages and disadvantages of IMRT and proton therapy for the treatment of esophageal cancer.
Challenges in Molecular Monitoring for CML Treatment Response
This video examines the challenge in optimizing and standardizing molecular monitoring for patients with chronic myeloid leukemia.
Avoiding Undertreatment, Overtreatment in Geriatric Breast Cancer Patients
This video reviews how to ensure that older breast cancer patients are receiving the most appropriate care and highlights population studies that can help inform individual treatment decisions.
Selecting Safe Chemotherapy Regimens in Older Breast Cancer Patients
This video reviews the evidence for safe and effective chemotherapy regimens in older patients with breast cancer and highlights the need for geriatric assessment in this population.
Vaccines to Prevent High-Grade Glioma
This video examines current research on the use of vaccines in low-grade glioma for the prevention of high-grade disease.
Biomarkers Could Predict Bladder Cancer Progression
This video examines a study that used liquid biopsies to monitor disease progression in patients with bladder cancer.
Immunotherapeutic Agents in Breast Cancer
This video reviews the latest trials and research on immunotherapeutic agents being tested in breast cancer.
MicroRNA Signature Predicted Breast Cancer Survival, Bone Metastasis
This video highlights a novel scoring system using microRNA signatures that predicted poor overall survival and bone metastasis in patients with luminal A breast cancer.
Marker May Predict Immunotherapy Benefit in High-Risk Neuroblastoma
This video examines how a specific combination of KIR/KIR-ligand genotypes in high-risk neuroblastoma patients may be predictive of outcomes when adding dinutuximab to isotretinoin.
CAR T-Cell Therapy Yields High Response Rate in Aggressive Lymphoma
This video reviews results of the ZUMA-1 trial, which tested the CAR T-cell therapy axicabtagene ciloleucel in patients with advanced non-Hodgkin lymphoma.
Prostate Cancer Death Linked With Shorter Sleep Duration
This video examines results of a study that found that shorter sleep duration was linked with an increased risk of death among patients with prostate cancer.
Adding Indoximod to Pembrolizumab Improved Response Rate in Advanced Melanoma
This video examines phase II results of a single-arm trial that tested checkpoint inhibition plus the IDO–pathway inhibitor indoximod in patients with melanoma.
Copanlisib Yields Responses in Relapsed/Refractory Non-Hodgkin Lymphoma
This video reviews results of the phase II CHRONOS-1 trial, a single-arm study evaluating the investigational agent copanlisib in patients with relapsed or refractory indolent non-Hodgkin lymphoma.
FGFR Inhibitor Shows Preclinical Activity in Breast Cancer
This video highlights preclinical activity of a novel FGFR inhibitor that has been tested alone and in combination with antihormonal therapy in breast cancer cell lines.
Treatment of Gastroesophageal Junction Carcinoma
This video reviews first- and second-line treatment options for patients with carcinoma of the gastroesophageal junction.