Future Perspectives in the Treatment and Management of Patients With EGFR-Mutated NSCLC
October 30th 2023Misako Nagasaka, MD, PhD, and Kristen Neumann, DNP, FNP-C, emphasize the importance of patient education, discussing how understanding the biological reasons behind treatments for EGFR-mutated non-small cell lung cancer and their side effects can lead to better outcomes, and highlighting the need for collaborative care and clear communication.
ASCEMBL: Recent Data Updates for Asciminib in CML
Charles A. Schiffer, MD, reviews clinical trial data for asciminib in chronic myeloid leukemia and highlights financial toxicity concerns.
Potential Role of Olverembatinib in CML
The expert panel discusses the potential role of olverembatinib in the chronic myeloid leukemia treatment landscape.
Goals of Treatment for Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia (R/R CLL)
October 27th 2023Medical expert discusses that when managing relapsed or refractory chronic lymphocytic leukemia, the goals are similar to first-line therapy, and he emphasizes using BCL-2 and BTK inhibitors, guided by factors such as previous therapies, patient preferences, and comorbidities.
Clinical Case Scenario: Managing a Diagnosis of Atrial Fibrillation
October 27th 2023Experts discuss the management of a patient with chronic lymphocytic leukemia who experienced adverse effects such as joint pain and atrial fibrillation while on treatment with ibrutinib, emphasizing the role of cardio-oncology and considering a switch to a second-generation BTK inhibitor for better safety and fewer drug interactions.
Outcomes After Biochemical or Clinical Progression in Patients with MM
Jeffrey A. Zonder, MD, reviews data on patient outcomes following biochemical or clinical progression in multiple myeloma.
Cross Q&A: Efficacy of CAR T-Cell Therapy in MM
The expert panel discusses the efficacy and durability of response of ciltacabtagene autoleucel in patients with multiple myeloma.
Amivantamab for Patients With NSCLC and an EGFR Exon 20 Mutation
October 23rd 2023Kristen Neumann, DNP, FNP-C, emphasizes the efficacy of the drug amivantamab for patients with EGFR exon 20 mutations, explaining the challenges of unique skin rashes, but highlighting the importance of teamwork in effectively managing and treating these adverse skin effects.
Olverembatinib in Patients with Pretreated/Refractory CML
Moaath Mustafa Ali, MD, MPH, reviews data on olverembatinib in patients with heavily pretreated/refractory chronic myeloid leukemia.
Treatment Considerations for Ponatinib in Patients With CML
Expert perspectives on treatment considerations for ponatinib in patients with chronic myeloid leukemia.
CARTITUDE-4: Cilta-Cel in Lenalidomide-Refractory MM
Jack Khouri, MD, discusses phase 3 results from the CARTITUDE-4 study investigating ciltacabtagene autoleucel in patients with lenalidomide-refractory multiple myeloma.
Cross Q&A: Treatment Considerations for Ixa-Pom-Dex in Multiple Myeloma
Following a review of data from the ALLIANCE A061202 study, experts on multiple myeloma discuss treatment considerations for patients being treated with ixazomib, pomalidomide, and dexamethasone.
The Role of Combination Venetoclax and BTKi Therapy for Firstline Treatment of CLL
October 20th 2023Ricardo Parrondo, MD, discusses the potential of combining BTK and BCL2 inhibitors in chronic lymphocytic leukemia treatment, emphasizing their synergistic effect and cautioning against use in frail patients or those with cardiovascular comorbidities, while Pooja Advani, MBBS, MD, stresses the importance of medical history and risk stratification, especially regarding cardiovascular adverse effects.