Opinion|Videos|March 31, 2025
CAR T in High-Risk DLBCL: Making the Right Choice in Aggressive Disease
Panelists discuss that when selecting a chimeric antigen receptor T-cell (CAR T) product for a patient with an aggressive clinical course and eligibility for cellular therapy, key considerations include urgency, toxicity risks, and efficacy. Factors such as time to manufacture, cytokine release syndrome/immune effector cell–associated neurotoxicity syndrome rates, long-term remission data, and antigen specificity guide decision-making.
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Episodes in this series
Video content above is prompted by the following:
- Given the aggressive clinical course and patient eligibility for cellular therapy and considering the urgency, toxicity risks, and efficacy profiles, what factors would guide your choice between available CAR T products?
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