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Opinion|Videos|March 31, 2025

IO-IO vs IO-TKI: Expert Approaches to First-Line RCC Treatment Selection

Author(s)Hans Hammers, MD, PhD, Thomas Hutson, DO, PharmD, PhD, FACP, Hannah Dzimitrowicz McManus, MD

Experts discuss their approaches to first-line renal cell carcinoma treatment selection, comparing immunotherapy (IO)-IO vs IO-tyrosine kinase inhibitor strategies.

Episodes in this series

EP. 1 CLEAR Trial Insights on Lenvatinib Plus Pembrolizumab: Depth of Response and Clinical Outcomes in Advanced RCC

EP. 1 CLEAR Trial Insights on Lenvatinib Plus Pembrolizumab: Depth of Response and Clinical Outcomes in Advanced RCC

EP. 2 Tumor Burden Impact on Postprogression Survival: Optimizing Strategies for Maximum Response in RCC

EP. 2 Tumor Burden Impact on Postprogression Survival: Optimizing Strategies for Maximum Response in RCC

EP. 3 From Initial Response to Long-Term Outcomes: Optimizing RCC Treatment Strategies Across the Care Continuum

EP. 3 From Initial Response to Long-Term Outcomes: Optimizing RCC Treatment Strategies Across the Care Continuum

EP. 4 From IMDC Risk Assessments to Sequencing Strategies: Clinical Implications From CLEAR Post Hoc Analyses

EP. 4 From IMDC Risk Assessments to Sequencing Strategies: Clinical Implications From CLEAR Post Hoc Analyses

EP. 5 Risk Score Stability and Post Lenvatinib Plus Pembrolizumab Treatment Selection in RCC

EP. 5 Risk Score Stability and Post Lenvatinib Plus Pembrolizumab Treatment Selection in RCC

EP. 6 Clinical Pearls: Synthesizing Risk Assessment and Response Patterns in Advanced RCC Management

EP. 6 Clinical Pearls: Synthesizing Risk Assessment and Response Patterns in Advanced RCC Management

EP. 7 IO-IO vs IO-TKI: Expert Approaches to First-Line RCC Treatment Selection

EP. 7 IO-IO vs IO-TKI: Expert Approaches to First-Line RCC Treatment Selection

EP. 8 KEYMAKER-U03: Lenvatinib Plus Belzutifan Emerges as a Promising Option in Advanced RCC and New Directions From ASCO GU 2025

EP. 8 KEYMAKER-U03: Lenvatinib Plus Belzutifan Emerges as a Promising Option in Advanced RCC and New Directions From ASCO GU 2025

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