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Opinion|Videos|December 11, 2024

Clinical Data Supporting CAR T in Earlier Lines: Updates From the CARTITUDE-1, CARTITUDE-4, and KarMMa-3 Trials

Author(s)Binod Dhakal, MD, MS, Jean Esselmann, RN , Larry Fitzgerald

Panelists discuss how clinical trial data from CARTITUDE-1, CARTITUDE-4, and KarMMa-3 demonstrate the efficacy of CAR T therapies cilta-cel and ide-cel in multiple myeloma, comparing their real-world outcomes and considering patient-specific factors for treatment selection.

Episodes in this series

3 experts in this video

EP. 1 A High-Risk Myeloma Patient’s Path to CAR T: Personal and Clinical Perspectives

3 experts in this video

EP. 2 Behind the Scenes: Patient Education and Decision-Making for CAR T

3 experts in this video

EP. 3 Clinical Data Supporting CAR T in Earlier Lines: Updates From the CARTITUDE-1, CARTITUDE-4, and KarMMa-3 Trials

3 experts in this video

EP. 4 The Real-World Logistics of CAR T Therapy: Financial and Practical Considerations

3 experts in this video

EP. 5 From Collection to Infusion: Comprehensive CAR T Treatment and Management Strategies From CAR T Specialists

3 experts in this video

EP. 6 The Post–CAR T Journey: Long-Term Monitoring, Multidisciplinary Care, and Continuous Patient Support

3 experts in this video

EP. 7 Life After CAR T: Patient and Clinical Perspectives on the Promise of CAR T in Multiple Myeloma

Video content above is prompted by the following:

Let’s start by discussing the treatment landscape and data with CAR T therapy in multiple myeloma. Please highlight pivotal data:
CARTITUDE-1/CARTITUDE-4
KarMMa-3
In which patients do you consider cilta-cel vs ide-cel? Has real-world practice reflected efficacy and safety data from these trials?

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