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Opinion|Videos|August 1, 2024

ctDNA Testing in a CRC Clinical Scenario

Author(s)Scott Kopetz, MD, PhD, FACP, Arvind Dasari, MD, MS, Jing Yi, PA

The panel examines a clinical scenario, detailing their approach to circulating tumor DNA testing, including turnaround times, and providing insights on patient counseling.

Episodes in this series

4 KOLs are featured in this panel.

EP. 1 Overview of colorectal cancer and its management

4 KOLs are featured in this panel.

EP. 2 Background on Colorectal Cancer Screening and its Role in Patient Care

4 KOLs are featured in this panel.

EP. 3 Circulating Tumor DNA Detection Techniques

4 KOLs are featured in this panel.

EP. 4 Describing the Value of ctDNA in Clinical Practice

4 KOLs are featured in this panel.

EP. 5 Clinical study of ctDNA-based MRD detection and INTERCEPT program update

4 KOLs are featured in this panel.

EP. 6 Recent findings from BESPOKE

4 KOLs are featured in this panel.

EP. 7 Incorporating ctDNA-Based MRD Testing and Study Findings Into Clinical Practice

4 KOLs are featured in this panel.

EP. 8 Key Considerations for Selection of ctDNA Detection Methods

4 KOLs are featured in this panel.

EP. 9 Clinical Utility of ctDNA Testing

4 KOLs are featured in this panel.

EP. 10 Barriers to Implementing ctDNA Testing

4 KOLs are featured in this panel.

EP. 11 ctDNA Testing in a CRC Clinical Scenario

4 KOLs are featured in this panel.

EP. 12 ctDNA to Inform Adjuvant Therapy and the CIRCULATE Trial

4 KOLs are featured in this panel.

EP. 13 Interpreting and Communicating ctDNA Results

4 KOLs are featured in this panel.

EP. 14 Addressing Gaps in ctDNA Testing

4 KOLs are featured in this panel.

EP. 15 Exploring the Future of ctDNA and Novel Treatment Strategies

Would you offer ctDNA testing?
- What is the turnaround time you would expect in this case for tumor-informed assay?
- What would your treatment recommendation be in the absence of ctDNA results?

Treatment slide questions:
- How would you counsel the patient?
- What change, if any, would you make to the treatment regimen?

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