News|Articles|February 11, 2026

Top 5 Surgical Takeaways From NCCN Breast Cancer Congress for Invasive Breast Cancer

Surgical updates for invasive breast cancer from the NCCN Breast Cancer meeting revealed insights on neoadjuvant endocrine therapy and SLNB omission.

The surgical management of invasive breast cancer continues to evolve toward a "less is more" approach, prioritizing de-escalation of local therapy when oncologically safe. At the recent NCCN 2026 Breast Cancer Congress, Meghan R. Flanagan, MD, MPH, a physician at Fred Hutch Cancer Center and assistant professor of surgery at the University of Washington School of Medicine, highlighted critical updates from the 2025 San Antonio Breast Cancer Symposium and recent clinical trials that are reshaping standard care.1 For oncology clinicians, these updates provide a framework for optimizing patient outcomes through personalized surgical and systemic strategies.