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Opinion|Videos|October 25, 2024

Management of Relapsed/Refractory Multiple Myeloma with Bispecifics: MonumenTAL-2, MajesTEC-1, and MagnetisMM-3 trials

Author(s)Saad Z. Usmani, MD, MBA, FACP, Rafael Fonseca, MD, Surbhi Sidana, MD

Panelists discuss recent updates in the management of relapsed/refractory multiple myeloma, focusing on key studies such as MonumenTAL-2 for talquetamab, long-term follow-up data from the phase 1/2 MajesTEC-1 for teclistamab, and findings from MagnetisMM-3 regarding elranatamab.

Episodes in this series

$EP. 1 Current Landscape of Relapsed/ Refractory Multiple Myeloma$

EP. 1 Current Landscape of Relapsed/ Refractory Multiple Myeloma

$EP. 2 Management of Relapsed/Refractory Multiple Myeloma with Bispecifics: MonumenTAL-2, MajesTEC-1, and MagnetisMM-3 trials$

EP. 2 Management of Relapsed/Refractory Multiple Myeloma with Bispecifics: MonumenTAL-2, MajesTEC-1, and MagnetisMM-3 trials

$EP. 3 Bispecifics in Relapsed/ Refractory Multiple Myeloma: Combination Strategies, Stepping Up, and Treatment Dose Considerations$

EP. 3 Bispecifics in Relapsed/ Refractory Multiple Myeloma: Combination Strategies, Stepping Up, and Treatment Dose Considerations

$EP. 4 Treatment Sequencing Strategies for Patients with Relapsed/ Refractory Multiple Myeloma$

EP. 4 Treatment Sequencing Strategies for Patients with Relapsed/ Refractory Multiple Myeloma

$EP. 5 Strategies for Community Adoption of Bispecifics into Treatment of Relapsed/ Refractory Multiple Myeloma$

EP. 5 Strategies for Community Adoption of Bispecifics into Treatment of Relapsed/ Refractory Multiple Myeloma

Video content above is prompted by the following:

Comment on the recent updates surrounding the management of R/R MM with bispecifics and bispecific combination therapies:

MonumenTAL-2 for talquetamab (Schinke CD et al. ASCO 2023 Abstract 8036)
Long-term follow-up from the phase 1/2 MajesTEC-1 for teclistamab (Garfall et al. ASCO 2024 Abstract 7540)
MagnetisMM-3for elranatamab in R/R MM (Lesokhin A, Nature 2023)

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