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|Articles|January 1, 2006

Oncology NEWS International

  • Oncology NEWS International Vol 15 No 1
  • Volume 15
  • Issue 1

Trial of Tykerb for HER2-Positive Breast Cancer Brain Mets Begins

SAN ANTONIO—GlaxoSmithKline has announced the initiation of a global multicenter phase II trial (known as EGF 105084) to evaluate Tykerb (lapatinib) for the treatment of ErbB2 (HER2)-overexpressing breast cancer that has metastasized to the brain. Tykerb is an orally bioavailable small molecule that potently inhibits two receptors, ErbB2 and ErbB1. It is currently in development as a first-line treatment for ErbB2-overexpressing breast cancer.

SAN ANTONIO—GlaxoSmithKline has announced the initiation of a global multicenter phase II trial (known as EGF 105084) to evaluate Tykerb (lapatinib) for the treatment of ErbB2 (HER2)-overexpressing breast cancer that has metastasized to the brain. Tykerb is an orally bioavailable small molecule that potently inhibits two receptors, ErbB2 and ErbB1. It is currently in development as a first-line treatment for ErbB2-overexpressing breast cancer.

Articles in this issue

almost 20 years ago

FDA Approves Nexavar for Use in Advanced Kidney Cancer

almost 20 years ago

Avastin Benefits Metastatic Breast Cancer

almost 20 years ago

Amgen to Acquire Abgenix

almost 20 years ago

Better Prognosis for ‘Elsewhere' Local Breast Ca Recurrences

almost 20 years ago

Herceptin/Taxotere Ups DFS in Early HER2+ Breast Ca

almost 20 years ago

NIH 2006 Budget Is Likely to Be Lower Than in 2005

almost 20 years ago

Amooranin, a Plant Compound, Shows Potential as Cancer Treatment

almost 20 years ago

Mesenchymal Stem Cell Transplantation Potential Novel Treatment for Patients With Severe Graft-vs-Host-Disease

almost 20 years ago

FDA Launches 7 Initiatives With European Drug Regulators

almost 20 years ago

Taxanes Comparable as Adjuvant Therapy of Breast Cancer; Weekly Paclitaxel More Effective Than q3wk

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Michelle L. Taylor, ANP-BC; Emely Alfaro, DNP, RN, CNS, OCN; Paige Griffith, CRNP; Beth Sandy, MSN, CRNP, FAPO

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