Maximizing Control via Radiation in High-Risk and Recurrent Breast Cancer

At the American College of Radiation Oncology 2026 Radiation Oncology Summit, J. Isabelle Choi, MD, presented a comprehensive overview of strategies to improve outcomes in locoregionally advanced or recurrent breast cancer.¹ As advances in early detection and multimodality therapy improve overall survival, clinicians are increasingly encountering the challenge of managing isolated locoregional recurrences and high-risk nodal involvement. Choi’s presentation offered actionable guidance for radiation oncologists on dose escalation for internal mammary nodes (IMNs) and supraclavicular (SCV) nodes as well as technical and clinical considerations for safe breast reirradiation. Here are the top 5 takeaways for radiation oncologists based on her presentation.