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Opinion|Videos|January 10, 2025

Understanding the CAR-T Treatment Process

Author(s)Sagar Lonial, MD, FACP, FASCO, Ajay K. Nooka, MD, Nisha Joseph, MD

Panelists discuss which patients are considered for CAR-T therapy in second-line treatment for relapsed/refractory multiple myeloma (R/R MM) (cilta-cel vs ide-cel), describe the specific criteria and institutional guidelines used to determine patient eligibility, and explore how non-medical factors like such as location and financial considerations impact patient selection, while also outlining the typical CAR-T referral process from community physician outreach to patient evaluation and selection.

Episodes in this series

$EP. 1 Exploring CAR-T Therapy in Early Lines of Relapsed/Refractory Multiple Myeloma$

EP. 1 Exploring CAR-T Therapy in Early Lines of Relapsed/Refractory Multiple Myeloma

EP. 2 Patient Selection and Referral Eligibility for CAR-T Therapy

EP. 2 Patient Selection and Referral Eligibility for CAR-T Therapy

EP. 3 Understanding the CAR-T Treatment Process

EP. 3 Understanding the CAR-T Treatment Process

EP. 4 CAR-T Therapy: Approach to Bridging

EP. 4 CAR-T Therapy: Approach to Bridging

EP. 5 Care Coordination and Transition Strategies for CAR-T Therapy

EP. 5 Care Coordination and Transition Strategies for CAR-T Therapy

EP. 6 CAR-T Therapy in Early Lines of R/R MM: Clinical Scenario Discussion and Key Takeaways

EP. 6 CAR-T Therapy in Early Lines of R/R MM: Clinical Scenario Discussion and Key Takeaways

EP. 7 Key Takeaways in CAR-T Therapy for Multiple Myeloma

EP. 7 Key Takeaways in CAR-T Therapy for Multiple Myeloma

Video content above is prompted by the following:

Which patients do you think about consider for CAR-T in second-line treatment for R/R MM (cilta-cel vs ide-cel)?
Can you describe the specific criteria/institutional guidelines used to determine patient eligibility for CAR-T referral?
How do non-medical factors (location, money, etc) impact patient selection?
Walk us through the typical CAR-T referral process at your institution, - from the initial community physician outreach to the patient evaluation and selection.

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