April 11th 2024
Combining rintatolimod with pembrolizumab may confer a synergistic effect in patients with recurrent ovarian cancer.
The Latest on Acute Lymphocytic Leukemia
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A Focus on Acute Myeloid Leukemia
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Updates in Myelodysplastic Syndromes
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Equalizing Inequities™ in Multiple Myeloma Care: Shining a Light on Current Barriers and Opportunities for Improved Outcomes
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Community Practice Connections™: What’s Next for Patients with Breast Cancer, and How Can We Effectively Optimize PARP-, HER2/3-, and TROP2-Targeted Regimens in Treatment Plans?
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Show Me Your Care Plan™: Nursing Considerations for Applying the Latest Approaches Across Care Settings in Melanoma
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Patient, Provider and Caregiver Connection™: Addressing Patient Concerns During the Treatment and Management of HR+/HER2- Breast Cancer
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Breaking Down Biomarkers in Non–Small Cell Lung Cancer: A Case-Based Discussion for the Oncology Nurse
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Medical Crossfire®: Critical Questions on Diagnosis, Sequencing, and Selection of Systemic and Radioligand Therapy Options for Patients with GEP-NETs
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Medical Crossfire®: Expert Exchanges to Maximize Clinical Outcomes for Patients with CRPC Through Evidence-Based Personalized Therapy
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Community Practice Connections™: 16th Annual Interdisciplinary Prostate Cancer Congress® and Other Genitourinary Malignancies
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Patient, Provider, and Caregiver Connection: Addressing Pediatric and AYA Patient Concerns While Managing Hodgkin Lymphoma
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Go To PER in Chicago
May 31, 2024 - June 2, 2024
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The Top 10 Oncogenic Drivers in NSCLC for 2023: What You Need to Know on Tumor Testing, Targets, and Treatment Strategies to Move the Field Forward
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Patient, Provider, and Caregiver Connection™: Individualizing Care for Patients with Schizophrenia—Understanding Patient Challenges and the Role of Innovative Treatment
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Expert Illustrations & Commentaries™: Exploring the Mechanistic Rationale for Targeting FGFR2 and Pan-FGFR in CCA
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Oncology Consultations®: Next Generation SERDs—Key Data and Practical Takeaways for the Community Physician
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Live “Hot Seat”: Experts Face Your Hot-Button Questions on Maximizing PARP Inhibitors in Patients With CRPC
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Medical Crossfire®: Leveraging Multidisciplinary Teams in Early–Stage Breast Cancer When the Goal is Cure
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Everything You Need to Know About PARP Inhibitor Combinations in Prostate Cancer Care: Why? For Whom? And When?
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Expanding the Armamentarium of Actionable Mutations in NSCLC: Uncovering the Potential of CEACAM5 as a Therapeutic Target
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Multidisciplinary Management of TNBC: Immunotherapy, PARP, TROP2, Oh My!
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The 14th Asia-Pacific Primary Liver Cancer Expert Meeting
July 18 - 20, 2024
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23rd Annual International Congress on the Future of Breast Cancer® East
July 19-20, 2024
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Community Practice Connections™: 14th Annual International Symposium on Ovarian Cancer and Other Gynecologic Malignancies
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Advances In™: Targeting PSMA to Advance Diagnosis And Management Of Patients With Prostate Cancer
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Clinical Case Vignette Series: Integrating Recent Data into Practice to Improve Outcomes in Advanced Prostate Cancer
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Community Practice Connections™: 8th Annual School of Gastrointestinal Oncology®
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Community Practice Connections™: The Advent of TROP2-Targeted Treatment Approaches in HR+/HER2- Breast Cancer
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Show Me the Data™: Do We Have Sea Change for Novel Approaches in HR+/HER2- Breast Cancer? CDK, PI3K/AKT, ADC, and Next-Gen SERD Strategies Assessed
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NIH Consensus Panel's Recommendations for Ovarian Cancer Screening Revisited for Ob/Gyns
September 1st 1995SAN FRANCISCO--Enhanced concern by the medical community and by women themselves prompted the National Institutes of Health's Office of Medical Applications of Research to convene last year's consensus conference on ovarian cancer, Vicki Seltzer, MD, said at the annual meeting of the American College of Obstetricians and Gynecologists (ACOG).
Search for Ovarian Cancer Screen Must Look Beyond Ultrasound
August 1st 1995WASHINGTON--Only a screening test that can reliably find stage I tumors will have any real impact on overall ovarian cancer mortality, and transvaginal ultrasound does not appear to fulfill that requirement. Although the technique can detect stage I ovarian cancers, its specificity is not high enough to make it useful as a general screening test, Beth Y. Karlan, MD, said at the American Cancer Society National Conference on Gynecological Cancers.
PET May Be Used to Detect Recurrences Of Ovarian Cancer
August 1st 1995BALTIMORE--Some 60% to 80% of ovarian cancer patients recur after the first round of treatment, and "only about 15% of ovarian cancer patients who test positive at second-look laparotomy survive as long as 5 years," Karl F. Hubner, MD, of the University of Tennessee, Knoxville, said at a nuclear oncology conference sponsored by the Johns Hopkins Medical Institutions.
ODAC Recommends Accelerated FDA Approval of Ethyol for Cytoprotection
July 1st 1995ROCKVILLE, Md--The Food and Drug Administration's Oncologic Drugs Advisory Committee (ODAC) has voted unanimously to recommend accelerated approval of Ethyol (amifostine injection) as a cytoprotective agent against cumulative renal toxicities associated with cyclophosphamide (Cytoxan, Neosar) and cisplatin (Pla-tinol) in patients with advanced solid tumors of non-germ-cell origin.
Experts Debate Value of Whole Abdominal Radiation (WAR) Therapy in Ovarian Ca
July 1st 1995PARIS, France--Postoperative whole abdominal radiation (WAR) therapy has no place in the management of ovarian cancer, David Gershenson, MD, of the University of Texas M.D. Anderson Cancer Center, said in a debate at the American Radium Society meeting.
Algorithm Optimizes Value of CA125 II Screening for Ovarian Ca
June 1st 1995WASHINGTON--Applying a newly developed mathematical model to an updated version of a familiar tumor marker may increase the chance of finding ovarian cancers at an earlier stage, Robert C. Knapp, MD, said at the American Cancer Society Conference on Gynecological Cancers.
Better Ovarian Cancer Outcome With IP Cisplatin
June 1st 1995LOS ANGELES--Administration of cisplatin (Platinol) by the intraperitoneal rather than intravenous route to patients with optimally debulked stage III ovarian cancer reduced toxicity and improved survival by about 25%, David S. Alberts, MD, said at the ASCO meeting.
Book Review: Adjuvant Therapy of Cancer--VII
June 1st 1995This is the seventh in a well-known series of conference summaries, organized and edited by Dr. Salmon. A perusal of the contents of these volumes over the past two decades reveals the evolution of concepts related to combined-modality therapy
New Approach to Diagnosing High-Risk, Early-Stage Ovarian Cancer
June 1st 1995Swedish researchers have, for the first time, used a combination of methods to accurately diagnose high-risk patents with early-stage ovarian cancer, thereby identifying those who would benefit from more aggressive treatment.
Paclitaxel/Cisplatin Improves Survival In Advanced Ovarian Cancer
June 1st 1995LOS ANGELES--Using paclitaxel (Taxol) rather than cyclophosphamide in combination with cisplatin (Platinol) significantly increases both progression-free and overall survival in patients with advanced ovarian cancer, William P. McGuire, MD, said in his presentation at the plenary session of ASCO.
Retinoic Acid May Enhance Chemo In Ovarian Ca Cells
May 1st 1995SAN FRANCISCO--Retinoic acid appeared to enhance the efficacy of cisplatin (Platinol) and paclitaxel (Taxol) in two of three ovarian cancer cell lines tested, James R. Bosscher, MD, said in his poster presentation at the Society of Gynecologic Oncologists meeting.
Centocor CA 125 II, New Version of CA 125 Assay, Is Now Available
May 1st 1995MALVERN, Penn--Centocor Diagnostics has introduced Centocor CA 125 II, a second-generation radioimmunoassay for the management of ovarian cancer. The new assay, a more sensitive version of Centocor CA 125, uses the same tracer antibody, OC125, but a new capture antibody, M11, to measure serum CA 125 levels.
Ocean Organisms a Source of New Anticancer Drugs
May 1st 1995NEW YORK--The earth's oceans are yielding a multitude of new sources of anticancer and anti-HIV agents, possibly with unique mechanisms of action (see illustration on page 1). In only 8 years of operation, Pharma Mar, s.a. (Madrid, Spain) has developed a library of more than 20,000 marine samples and has isolated some 350 novel marine-based compounds, including 40 that have been patented.
New Docetaxel Ovarian Cancer Trial
May 1st 1995LISBON, Portugal--Encouraging news for women with platinum-resistant advanced ovarian cancer has emerged from a large phase II trial of docetaxel (Taxotere) conducted by the European Organization for Research and Treatment of Cancer (EORTC) Early Clinical Trials Group.
Study Shows No Reduced Cancer Risk in Women From Average Selenium Intake
May 1st 1995Unlike some animal, ecologic, case-control, and prospective studies that have associated higher selenium levels with reduced cancer risk, a large cohort study recently reported in the Journal of the National Cancer Institute found that selenium intake
Epidemiology of Cancer and Prevention Strategies
April 1st 1995Cancer epidemiology is the study of the distribution, determinants, and frequency of malignant disease in specific populations [1]. The objective is to define causative factors to formulate preventive strategies for control of the disease.
Try to Maintain Platinum Intensity in Low-Volume Ovarian Ca: McGuire
March 1st 1995PARIS--Physicians should strive to maintain intensive platinum therapy in women with low-volume ovarian cancer, urged William McGuire III, MD, of Emory University. "However, I don't think there's yet data to show that we need to crank
Clinical Trials Approved for Titan's AN-9 and its MDR Gene Therapy
March 1st 1995MENLO PARK, Calif--Ansan, Inc., an operating company of Titan Pharmaceuticals, has received FDA approval to start a phase I trial of its butyric acid derivative AN-9 in patients with solid tumors. In preclinical studies, AN-9 demonstrated broad anticancer activity and may have less toxicity than standard chemotherapeutic agents, the company said.
FDA Advisory Board Wants to See Further Analyses of Ethyol Trials
February 1st 1995ROCKVILLE, Md--The FDA's Oncologic Drugs Advisory Committee has declined to recommend Ethyol (amifostine injection, U.S. Bioscience, Inc.) for approval at this time. The drug is being considered as a cytoprotective agent against both the acute and cumulative hematologic and renal toxicities associated with alkylating agents such as cyclophosphamide (Cytoxan, Neo-sar) and platinum agents such as cisplatin (Platinol) in patients with ovarian cancer.
The Management of Early Ovarian Cancer
Approximately one third of patients with epithelial ovarian cancer present with localized or early-stage disease. Prognostic features identify certain subsets of patients with good risk characteristics who do not require adjuvant
Commentary (Markman): The Management of Early Ovarian Cancer
February 1st 1995The paper by Schilder et al is an outstanding review of the current status of the management of women with early-stage ovarian cancer. As the paper makes clear, despite the efforts of numerous cancer research groups around the world, an optimal treatment strategy for early-stage ovarian cancer has yet to be defined.
Commentary (Thigpen): The Management of Early Ovarian Cancer
February 1st 1995Schilder and colleagues have provided a detailed and excellent review of the management of early ovarian carcinoma. Several areas of the review deserve comment and will be considered in the following order: staging and prognostic factors, conservative surgery, and adjuvant therapy.