March 22nd 2023
Findings from a cohort of the Childhood Cancer Survivor Study identify a prediction model that may accurately identify childhood cancer survivors at varying risks of late kidney failure.
February 25th 2023
Sperm Banking Underutilized in Adolescent Cancer PatientsOctober 12th 2017
Fertility preservation through sperm banking was underutilized among adolescent males newly diagnosed with cancer, according to the results of a recent observational study. Only about one-half of adolescents surveyed in the study attempted sperm banking.
Screening Tool May Predict Subsequent Distress Among Parents of Children With CancerOctober 11th 2017
A parent’s score on the electronic Psychosocial Assessment Tool following the diagnosis of cancer in a child was predictive of future levels of parental distress, according to the results of a new study.
Health Insurance Coverage Has Little Effect on Childhood Cancer SurvivalSeptember 17th 2017
Children covered by Medicaid when diagnosed with cancer have similar survival rates compared with children with private insurance, according to a new study. Evidence shows a slightly increased risk of cancer death among uninsured children, which may be related to a more advanced stage at diagnosis.
FDA Approves First Gene Therapy for Pediatric LeukemiaSeptember 1st 2017
The FDA has approved the first gene therapy available in the United States, tisagenlecleucel (Kymriah), for the treatment of pediatric and young adult patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia.
New Biomarker Assay May Help Predict PFS in Neuroblastoma PatientsJuly 10th 2017
Researchers have discovered a way to test for multiple neuroblastoma-associated genes simultaneously, which may help to improve definition of disease status in patients with relapsed/refractory neuroblastoma.
Inflammation Linked to Cognitive Difficulties in Childhood ALL SurvivorsMay 8th 2017
Female survivors of childhood acute lymphoblastic leukemia were at risk for neurocognitive impairment and were more susceptible to the effects of sleep disturbance and fatigue compared with their male counterparts.
Leucocyte Marker in Pediatric ALL Linked With Relapse-Free SurvivalMarch 20th 2017
During maintenance therapy for childhood ALL, there was a general increase in DNA-incorporated thioguanine nucleotides (DNA-TGN), and this increase was associated with a lower frequency of disease relapse.
Optimizing the Benefit of CNS Radiation Therapy in the Pediatric Population-PART 1: Understanding and Managing Acute and Late Toxicities
Minimizing late treatment toxicities in these patients remains an important priority due to both the young age of the patients and the high cure rate that can be achieved.
Optimizing the Benefit of CNS Radiation Therapy in the Pediatric Population-PART 2: Novel Methods of Radiation Delivery
In this article we discuss the specifics of refining current strategies for radiation delivery, as well as new and up-and-coming heavy particle techniques and radiotherapeutics.
Reduced, Compressed Chemotherapy Fails in Pediatric Germ Cell TumorsMarch 11th 2017
Event-free survival was not maintained in children and adolescents with intermediate-risk malignant germ cell tumors when cisplatin-based chemotherapy was reduced from four to three cycles and compressed from 5 to 3 days per cycles.
Musculoskeletal Manifestations of Pediatric ALL Delayed DiagnosisJanuary 13th 2017
Presentation with musculoskeletal manifestations as the only symptom in pediatric B-cell acute lymphoblastic leukemia was significantly associated with diagnostic delay. However, this delay did not affect patient prognosis.