February 14th 2025
Prophylactic defibrotide conferred more ICU admissions and higher mortality among high-risk pediatric patients who underwent prior HSCT.
Fighting Disparities and Saving Lives: An Exploration of Challenges and Solutions in Cancer Care
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Epithelioid Sarcoma: Applying Clinical Updates to Real Patient Cases
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Collaborating Across the Continuum®: Identifying and Treating Epithelioid Sarcoma
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Mastering Epithelioid Sarcoma: Enhancing Diagnostic Precision and Tailoring Treatment Strategies
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Clinical Showcase™: Selecting the Best Next Steps for a Patient with Epithelioid Sarcoma
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High-Dose Chemo Before RT Results in High Survival in Pediatric Brain Tumors
June 10th 2014High-dose chemotherapy plus conventional radiotherapy resulted in a high 3-year overall survival in children and adolescents with newly diagnosed medulloblastoma and supratentorial primitive neuroectodermal tumor.
Leukemia Risk for Children Near Power Lines?
February 28th 2014Contrary to some previous research as well as popular belief, living underneath or near to power lines as a child may not have any notable effect on childhood leukemia risk, according to a new case-control study conducted in the United Kingdom.
In Pediatric AML, CD33 Targeting Agent Improved EFS, Risk of Relapse
December 11th 2013Treatment with gemtuzumab ozogamicin improved the event-free survival in children and adolescents with acute myeloid leukemia by reducing the risk of relapse among those able to achieve remission, according to trial results presented at the 2013 ASH meeting.
Inherited Mutation Linked to Development of Pediatric ALL
September 21st 2013A mutation of the PAX5 gene has been found to play an important role in inherited cases of B-cell precursor acute lymphoblastic leukemia (B-ALL). The mutation was isolated in two unrelated families with high propensity for B-ALL.
Dasatinib Shows Promise for Pediatric CML, ALL Patients
September 13th 2013A phase I study of dasatinib in children and adolescents with chronic myeloid leukemia (CML) and other malignancies determined dosing for further studies and suggested the drug is well tolerated and effective in these patients.
Bisphosphonate Effective in Treating Osteonecrosis Pain in Pediatric ALL
June 24th 2013Use of the bisphosphonate pamidronate (Aredia) may be “more efficient” than standard regimens as palliative treatment for symptoms of acute symptomatic osteonecrosis in pediatric patients with acute lymphoblastic leukemia.
Methotrexate/Asparaginase Combo for Pediatric AML May Be Effective Salvage Therapy
March 19th 2013Combination chemotherapy with sequential administration of methotrexate and asparaginase was found to be effective salvage therapy in a small retrospective study of pediatric patients with relapsed or refractory acute myeloid leukemia (AML).
A Tale of Two Tumors: Pediatric and Adult Medulloblastoma
November 15th 2012Future studies of adult medulloblastoma should include whole genome sequencing and identification of the tumorigenic cell origin of adult medulloblastoma. Ultimately, quality prospective trials are needed in adult medulloblastoma patients in order to optimize the management of this rare and complex disease.