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WASHINGTON-Oncology is in transition from its traditional methods of diagnosing and treating cancer to a reliance on molecular changes within cells-and the science behind this paradigm shift will lead to new drugs to attack precancerous conditions as well, several cancer researchers said at a congressional briefing.

PHILADELPHIA-A study presented at the Oncology Nursing Society’s 26th Annual Congress in San Diego underscores the challenge of managing cancer-related fatigue: Fatigue frequently is part of a cluster of interrelated symptoms, such as pain, depression, and poor sleep quality.

SAN DIEGO-Power to shape health care policy and practice was on the minds of thousands of oncology nurses who attended the Oncology Nursing Society’s 26th Annual Congress. Roused by their leaders and a mariachi band marching down the aisle of the Convention Center at the opening session, more than 5,000 nurses from around the world proclaimed in unison, "We will be heard! We will be heard! We will be heard!"

BOSTON-Outpatient infusion units around the country have experienced soaring numbers of patients due to changes in reimbursement as well as increasingly complex cancer treatments. In a move that contributed to this growth, oncologists at the Massachusetts General Hospital (MGH), supported by the literature, began giving 2-hour infusions of pamidronate (Aredia®) for prevention of skeletal complications from several malignancies.

SAN FRANCISCO-Potentially therapeutic concentrations of ZD1839 (Iressa) inhibit phosphorylation in HER2-overexpressing breast tumor cell lines that coexpress HER1, Stacy Moulder, MD, Vanderbilt University Medical Center, said at the 37th Annual Meeting of the American Society of Clinical Oncology (ASCO).

TAMPA, Florida-A rehabilitation group program-Energy for Living With Cancer-has the ability to reduce fatigue-related distress and improve quality of life, according to program developer Sandra Holley, PhD, ARNP, a nurse scientist at the James A. Haley Veterans Administration Medical Center, Tampa. Dr. Holley presented her results in a poster session at the Oncology Nursing Society’s 26th Annual Congress.

HOUSTON-Cancer patients receiving aggressive treatment often face difficult decisions. Nurses will often help patients and their families through them-but the nurses may need support themselves, says a nurse who co-authored a study looking at nurse utilization of hospital ethics rounds.

PITTSBURGH-Two recent reports by the Health Resources and Services Administration spotlight a difficult situation in health care today, both for providers and patients. The agency’s 2000 "National Sample Survey of Registered Nurses" found a significant decline in the rate of increase for people entering nursing-from 14.2% between 1992 and 1996, to 4.1% between 1996 and 2000-at a time of greater population growth and aging.

INDIANAPOLIS-Transplant patients may maintain a central line for 6 months to a year. At high risk for infection, they must know how to take care of their line. But when do they learn? Teachable moments can be few and far between, according to Indiana University Hospital nurses who made a video to help solve the problem.

WASHINGTON-The tobacco wars continue in the nation’s capital. The Bush Administration has announced it will seek a settlement of the federal lawsuit against the tobacco industry, initiated during the Clinton Administration to recover profits the industry made through alleged fraudulent practices.

Written by Jimmie C. Holland, MD, and Sheldon Lewis, this book focuses on the "human effects" as opposed to the

AUSTIN, Texas-Although the nursing profession supports patient empowerment and self-determination in health care decision-making, patient requests for assisted dying raise difficult issues. A study reported at the Oncology Nursing Society’s 26th Annual Conference explored the symptom management strategies that some nurses use to either counter or preempt patient requests for help in dying.

WASHINGTON-Colorectal cancer patients with unresectable liver metastases responded better to a regimen of regional and systemic chemotherapy plus cytoreduction than to cytoreduction alone, said David Litvak, MD, of the John Wayne Cancer Institute, Santa Monica, and Century City Hospital, Los Angeles.

SAN DIEGO-Lead aprons, radiation badges, and patient laundry are not the normal concerns of nurses. But as new radioimmunotherapy agents are evaluated and introduced into practice, nurses will need to familiarize themselves with radiation safety precautions, said Patricia A. Kramer, RN, MSN, a San Francisco-based oncology nurse educator and consultant. Patient education and instruction throughout the whole process is key.

STONY BROOK, NY-The new Long Island Cancer Center at Stony Brook University is welcoming the community into a partnership in cancer research, John S. Kovach, MD, founding director of the Center, told ONI in an interview.

WASHINGTON-Witnesses at the first-ever Congressional hearing on hematologic cancers urged Congress to act on the recommendations of the Leukemia-Lymphoma-Myeloma Progress Review Group (LLM-PRG). This group, composed of more than 180 researchers, clinicians, patient advocates, industry representatives, and government officials, released its report last May.

BUFFALO, NY-A pain intensity assessment program undertaken at Roswell Park Cancer Institute has been successful in increasing staff assessment of pain and in promoting optimal pain management. Reporting at a poster session at the Oncology Nursing Society’s 26th Annual Congress, Jacqueline L. Massey, RN, MS, assistant director of nursing, described the development of the Center’s comprehensive program, known as the Fifth Vital Sign.

BUFFALO, NY-Former Roswell Park Cancer Institute (RPCI) faculty member J. Craig Venter, PhD, founder and president of Celera Genomics, returned to the Buffalo-based comprehensive cancer center to present the Institute’s Cori Lecture (see box).

If he needed more encouragement than the California verdict, Sen.Wyden (D-Ore) got it a week later when the National

Researchers at the University of Nebraska Medical Center/Nebraska Health System (UNMC/NHS) are investigating one of

PORTLAND, Oregon -Aerobic exercise may be more effective than resistance exercise in reducing cancer-related fatigue among patients taking catabolic steroids, according to a study presented at the Oncology Nursing Society’s 26th Annual Congress, held in San Diego.

SAN DIEGO-Susan A. Newton, RN, MS, AOCN, is an independent consultant based in Dayton, Ohio, who travels throughout Ohio, Indiana, and Kentucky teaching patients and colleagues, regionally and nationally, about cancer-related fatigue and pain management.

SAN FRANCISCO-A highly sensitive photon sensor has shown promise as a means of detecting early, subtle responses to neoadjuvant therapy among patients with soft tissue sarcomas, investigators from the Dana-Farber Cancer Institute reported at the 37th Annual Meeting of the American Society of Clinical Oncology (ASCO).

SAN DIEGO, California-The Workflow Information Systems for European Nursing Care (WISECARE) program is using information technology to foster knowledge sharing and to promote evidence-based nursing care among 15 European cancer centers.

At Memorial Sloan-Kettering Cancer Center, nurses are recruiting newly diagnosed cancer patients into a smoking cessation program. At Marshfield Clinic Cancer Care, Marshfield, Wisconsin, nurses are teaching phlebotomists how to do venous access device (VAD) blood draws. And at St. Joseph Medical Center, Towson, Maryland, nurses have made depression assessment part of standard oncology care.

Cancer patients are at high riskof potentially fatal blood clots

SAN FRANCISCO-In a phase II trial, recombinant human keratinocyte growth factor (rHuKGF, or KGF) significantly reduced severe mucositis and improved quality of life for patients with hematologic malignancies who underwent autologous peripheral blood progenitor cell transplantation.

WASHINGTON-With a Joint Commission on Accreditation of Healthcare Organizations (JCAHO) visit looming, nurses at George Washington University Hospital used the opportunity to implement a staff education program to improve pain assessment and management.

In the United States, tobacco use is the leading cause of preventable death. Exposure to environmental tobacco smoke (ETS)

The incidence of invasive aspergillosis is increasing parallel to the intensity of immunosuppressive and myelosuppressive anticancer treatments. Successful management is linked to an understanding of the