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Opinion|Videos|February 10, 2025

Approach to Metastatic Disease

Author(s)Rahul Gosain, MD, Rohit Gosain, MD, Virginia Kaklamani, MD, DSc

Panelists discuss how the approach to metastatic disease focuses on systemic therapy, as cancer has spread beyond its primary site. Treatment typically combines targeted therapy, immunotherapy, chemotherapy, and/or hormonal therapy based on cancer type and molecular profile. Goals shift toward extending survival, controlling symptoms, and maintaining quality of life rather than cure. Regular monitoring of treatment response and adverse effects guides ongoing care decisions.

Episodes in this series

EP. 1 Early-Stage Triple-Negative Breast Cancer

EP. 1 Early-Stage Triple-Negative Breast Cancer

EP. 2 Locally Advanced Triple-Negative Breast Cancer

EP. 2 Locally Advanced Triple-Negative Breast Cancer

EP. 3 Navigation of Triple-Negative Breast Cancer Treatment Toxicities

EP. 3 Navigation of Triple-Negative Breast Cancer Treatment Toxicities

EP. 4 Approach to Metastatic Disease

EP. 4 Approach to Metastatic Disease

EP. 5 Clinical Pros of Sacituzumab and T-DXd

EP. 5 Clinical Pros of Sacituzumab and T-DXd

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