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Opinion|Videos|February 10, 2025

Clinical Pros of Sacituzumab and T-DXd

Author(s)Rahul Gosain, MD, Rohit Gosain, MD, Virginia Kaklamani, MD, DSc

Panelists discuss how sacituzumab shows significant efficacy in triple-negative breast cancer, with improved progression-free and overall survival. It demonstrates particular benefit in pretreated patients and brain metastases cases. Trastuzumab deruxtecan (T-DXd) excels in HER2-positive breast cancer treatment, showing remarkable response rates and survival benefits, including in patients with brain metastases and those who progressed on prior therapies.

Episodes in this series

EP. 1 Early-Stage Triple-Negative Breast Cancer

EP. 1 Early-Stage Triple-Negative Breast Cancer

EP. 2 Locally Advanced Triple-Negative Breast Cancer

EP. 2 Locally Advanced Triple-Negative Breast Cancer

EP. 3 Navigation of Triple-Negative Breast Cancer Treatment Toxicities

EP. 3 Navigation of Triple-Negative Breast Cancer Treatment Toxicities

EP. 4 Approach to Metastatic Disease

EP. 4 Approach to Metastatic Disease

EP. 5 Clinical Pros of Sacituzumab and T-DXd

EP. 5 Clinical Pros of Sacituzumab and T-DXd

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