Nonimmune Adverse Effects: Managing Dysgeusia and Fatigue

Summary for Physicians:

Nonimmune Adverse Effects: Managing Dysgeusia and Fatigue

• Dysgeusia (altered taste):
• Common adverse effect, particularly with chemotherapy and immunotherapy

• Management:

• Recommend small, frequent meals with strong flavors (eg, citrus, mint).

• Suggest using plastic utensils to minimize taste alteration.

• Encourage good oral hygiene to reduce taste disturbances.
• Fatigue:
• Frequently reported, can be persistent and impact quality of life

• Management:

• Energy conservation techniques (eg, rest periods, prioritizing tasks)

• Exercise programs to improve stamina and reduce fatigue

• Monitor for underlying causes such as anemia or dehydration

• Address sleep hygiene and manage emotional stress

Challenges:

Both symptoms can be challenging to manage long term, requiring personalized strategies and regular assessment.