Optimizing Multidisciplinary Coordination for Successful Tarlatamab Implementation

EP: 1.ES-SCLC vs LS-SCLC: Critical Differences in Disease Burden and Patient Prognosis

EP: 2.Current Treatment Paradigm: Evolution of First-Line Therapy for ES-SCLC

EP: 3.Addressing Critical Unmet Needs in ES-SCLC Patient Management

EP: 4.Emerging Clinical Trials: Novel Approaches in Second-Line ES-SCLC

EP: 5.Institutional Implementation: Setting Up Tarlatamab Administration

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EP: 6.Optimizing Multidisciplinary Coordination for Successful Tarlatamab Implementation

EP: 7.Patient Selection Criteria: Identifying Appropriate Candidates for Tarlatamab

EP: 8.Tarlatamab Administration and Postinfusion Monitoring

EP: 9.Essential Patient and Caregiver Education for Tarlatamab Treatment Success

EP: 10.Neurological Toxicity Recognition: ICANS Assessment and Management

EP: 11.CRS Recognition and Intervention: Timing and Clinical Features

EP: 12.Nonimmune Adverse Effects: Managing Dysgeusia and Fatigue

EP: 13.Differential Toxicity Profile: Tarlatamab vs Traditional Cytotoxic Therapies

EP: 14.Standardized Toxicity Grading: Institutional Protocols for CRS and ICANS

EP: 15.Future Research Priorities: Optimizing Tarlatamab Administration and Toxicity Management

EP: 16.Seamless Transitions: Managing the Inpatient to Outpatient Care Continuum

EP: 17.Complex ES-SCLC Case: Tarlatamab Management Through Toxicity to Clinical Benefit

Summary for Physicians:

Optimizing Coordination for Tarlatamab Administration:

• Multidisciplinary Team (MDT) Collaboration:
• Regular communication between oncology, pharmacy, neurology, and nursing to align on treatment plans.
• Shared care protocols to ensure consistency in patient monitoring, especially for immune-related adverse effects.
• Joint decision-making for pretreatment screening and addressing adverse events promptly.
• Pharmacy Role:
• Ensure proper drug handling and dosing protocols are followed.
• Support with timely drug availability and managing potential supply chain issues.
• Neurology Input:
• Monitor for any neurological symptoms (eg, seizures, encephalopathy) and adjust management as needed.

General Approach:

• Establish clear workflows for patient care, from infusion to follow-up, ensuring all team members are aware of each stage of treatment.

Encourage routine MDT meetings to review patient progress and adapt as necessary.