Seamless Transitions: Managing the Inpatient to Outpatient Care Continuum

EP: 1.ES-SCLC vs LS-SCLC: Critical Differences in Disease Burden and Patient Prognosis

EP: 2.Current Treatment Paradigm: Evolution of First-Line Therapy for ES-SCLC

EP: 3.Addressing Critical Unmet Needs in ES-SCLC Patient Management

EP: 4.Emerging Clinical Trials: Novel Approaches in Second-Line ES-SCLC

EP: 5.Institutional Implementation: Setting Up Tarlatamab Administration

EP: 6.Optimizing Multidisciplinary Coordination for Successful Tarlatamab Implementation

EP: 7.Patient Selection Criteria: Identifying Appropriate Candidates for Tarlatamab

EP: 8.Tarlatamab Administration and Postinfusion Monitoring

EP: 9.Essential Patient and Caregiver Education for Tarlatamab Treatment Success

EP: 10.Neurological Toxicity Recognition: ICANS Assessment and Management

EP: 11.CRS Recognition and Intervention: Timing and Clinical Features

EP: 12.Nonimmune Adverse Effects: Managing Dysgeusia and Fatigue

EP: 13.Differential Toxicity Profile: Tarlatamab vs Traditional Cytotoxic Therapies

EP: 14.Standardized Toxicity Grading: Institutional Protocols for CRS and ICANS

EP: 15.Future Research Priorities: Optimizing Tarlatamab Administration and Toxicity Management

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EP: 16.Seamless Transitions: Managing the Inpatient to Outpatient Care Continuum

EP: 17.Complex ES-SCLC Case: Tarlatamab Management Through Toxicity to Clinical Benefit

Summary for Physicians:

Best Practices for Transitioning From Inpatient to Outpatient Care:

• Clear communication:
• Ensure care coordination between inpatient and outpatient teams for a smooth transition.

• Provide detailed discharge instructions, including follow-up plans, medications, and warning signs of complications.
• Outpatient visit frequency:
• Initially, schedule visits weekly or biweekly post discharge for close monitoring.

• After stabilization, transition to monthly visits, adjusting based on patient condition.
• Key monitoring strategies:
• Monitor for toxicity (eg, cytokine release syndrome, neurological issues) and infection risks

• Regular assessments of vital signs, lab tests, and adverse effect management

• Ensure patient adherence to treatment protocols and ongoing symptom tracking

Challenges:

Coordinating care across multiple providers and ensuring patient adherence with follow-up plans.