Articles by Natalie Vokes, MD

The Role of Early Biomarker Testing in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this closing segment, Dr. Alexander Spira and Dr. Edward Kim reflect on key takeaways from the patient case discussions, with a focus on the importance of early and comprehensive biomarker testing in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Transitioning to Adjuvant Therapy in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Ticiana Leal discuss how to approach the transition from neoadjuvant therapy to the adjuvant setting in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Surgical Considerations After Neoadjuvant Therapy in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Natalie Vokes explore the impact of neoadjuvant targeted therapy on surgical planning and outcomes in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Defining Meaningful Outcomes in Neoadjuvant EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Edward Kim discuss which outcomes are most clinically meaningful when evaluating neoadjuvant targeted therapy in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Biopsy-Driven Neoadjuvant Planning in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira introduces a second patient case involving a 62-year-old woman with resectable stage IIIA EGFR-mutated non–small cell lung cancer (NSCLC), where the mutation was identified from an initial biopsy.

Counseling Persistence in EGFR-Mutated NSCLC Therapy
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Edward Kim discuss how to counsel patients who are hesitant to continue adjuvant therapy despite feeling well in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Long-Term Toxicity Management in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Ticiana Leal discuss strategies for monitoring and managing treatment-related adverse events over time in patients receiving adjuvant therapy for early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Motivating Treatment Persistence in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Natalie Vokes discuss how to effectively counsel patients on completing the full course of adjuvant therapy in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Patient Selection for Adjuvant Therapy in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Edward Kim discuss key considerations in selecting patients for adjuvant targeted therapy in early-stage EGFR-mutated non–small cell lung cancer (NSCLC), particularly those with multiple comorbidities.

Shared Decision-Making in Early-Stage EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira introduces the first patient case scenario, focusing on a 72-year-old man with resected stage IIB EGFR-mutated non–small cell lung cancer (NSCLC) who has completed adjuvant chemotherapy and is considering further treatment.

Driving Guideline-Aligned Care in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Ticiana Leal discuss variability in treatment selection for early-stage EGFR-mutated non–small cell lung cancer (NSCLC) and strategies to promote guideline-aligned care. Dr. Leal highlights that despite clear recommendations, differences in practice patterns persist, particularly in community settings.

Managing EGFR-TKI Toxicities in Early-Stage EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Edward Kim focus on the importance of adverse event management in patients receiving adjuvant EGFR tyrosine kinase inhibitors for early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Setting Expectations for Long-Term Therapy in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Natalie Vokes discuss how to effectively counsel patients starting adjuvant EGFR tyrosine kinase inhibitor therapy in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Neoadjuvant Decision-Making in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira is joined by Dr. Ticiana Leal, Dr. Edward Kim, and Dr. Natalie Vokes to discuss clinical decision-making around neoadjuvant therapy in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Multidisciplinary Coordination in EGFR-Mutated NSCLC Treatment Planning
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Ticiana Leal focus on the importance of multidisciplinary coordination in managing early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Biomarker Testing at Diagnosis in Early-Stage EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Edward Kim discuss the critical role of early and comprehensive biomarker testing in the management of early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Real-World Outcomes With EGFR-TKIs in Early-Stage EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Natalie Vokes examine how outcomes with adjuvant EGFR tyrosine kinase inhibitors translate from clinical trials into real-world practice in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Interpreting EGFR-TKI Evidence for Early-Stage EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Ticiana Leal discuss how clinicians interpret EGFR tyrosine kinase inhibitor (TKI) data across different clinical trials and apply these findings to early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

Osimertinib Across Stages: Shaping Early-Stage EGFR-Mutated NSCLC Care
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Dr. Alexander Spira and Dr. Edward Kim discuss how the clinical development of osimertinib across multiple disease stages has influenced treatment expectations in early-stage EGFR-mutated non–small cell lung cancer (NSCLC).

EGFR Biology and Treatment Selection Beyond PD-L1 in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA In this segment, Alexander Spira, MD, PhD, engages Natalie Vokes, MD, in a discussion on the distinct biology of EGFR-mutated non–small cell lung cancer and how it informs treatment decisions in the early-stage setting.

Neoadjuvant Strategies and Early Biomarker Testing in EGFR-Mutated NSCLC
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA NEADORA data highlights why early NGS guides resectable EGFR lung cancer care, favoring perioperative osimertinib and avoiding checkpoint inhibitors.

Evolving Adjuvant Therapy in Early-Stage EGFR-Mutated NSCLC: Insights From ADAURA
ByAlexander Spira, MD, PhD, FACP, FASCO,Ticiana Leal, MD,Natalie Vokes, MD ,Edward S. Kim, MD, MBA Experts explain how adjuvant osimertinib changes post-surgery EGFR lung cancer care, from rapid testing to real-world adherence.