BETA
Your AI-Trained Oncology Knowledge Connection!
Using Molecular Tools to Guide Breast Cancer Treatment
This video examines the use of molecular diagnostics for guiding adjuvant endocrine therapy in patients with breast cancer.
Latest Immunotherapy Approaches in Multiple Myeloma
This video highlights novel approaches using immunotherapies and vaccines for advancing treatment in multiple myeloma.
Surgical Management of Stage III (N2) Lung Cancer
This video reviews the role of surgery in patients with stage III (N2) non–small-cell lung cancer, highlighting some of the challenges in studying these patients and the need for multidisciplinary patient evaluations.
Does Radiotherapy in Unresectable Pancreatic Cancer Add Value?
This video reviews the conflicting data and perspectives regarding the use of radiotherapy in unresectable pancreatic cancer.
Second-Line Therapy Options in Metastatic Renal Cell Carcinoma
This video reviews the various treatment options for metastatic renal cell carcinoma in the second-line setting, including considerations for different toxicity profiles.
First-Line Treatment of Metastatic Renal Cell Carcinoma
This video reviews the first-line treatment of metastatic renal cell carcinoma, including for those patients who are ineligible for interleukin-2.
Tackling Endocrine Resistance in Breast Cancer
This video reviews the mechanisms of acquired and upfront endocrine resistance in estrogen receptor–positive breast cancer as well as research into strategies for overcoming this resistance.
Is Pseudoprogression in Lung Cancer Real?
This video reviews pseudoprogression in non–small-cell lung cancer, including the incidence of this phenomenon and treatment considerations when it arises.
Chemotherapy Decision-Making in Early Breast Cancer
This video discusses chemotherapy decision-making in early-stage breast cancer, and reviews tools such as PREDICT 2.0 and the MammaPrint 70-gene assay that can help guide treatment.
PD-L1 Testing in Lung Cancer
This video reviews the use of PD-L1 testing in selecting patients for frontline lung cancer treatment with pembrolizumab and examines which patients might not be appropriate for immunotherapy.
Immunotherapy Resistance in Pancreatic Cancer
This video examines the role of immunotherapy in pancreatic cancer, highlighting the resistance to novel treatments in this setting and trials attempting to confront this problem.
Planned Radiation in Axillary Management of Breast Cancer
This video examines how planned radiation will impact management of the axilla in breast cancer patients undergoing mastectomy.
Management of Resectable Pancreatic Cancer
This video examines the management of resectable pancreatic cancer, including how this type of disease is best defined, the latest standard of care in the adjuvant setting, and emerging trends in surveillance.
Maintenance Therapy in Mantle Cell Lymphoma
This video reviews different strategies for maintenance therapy in mantle cell lymphoma, as well as highlighting upcoming research in this setting.
Targeting Genetic Drivers of Rare Genitourinary Cancers
This video reviews new studies examining the genetic drivers of three rare genitourinary cancers: von Hippel-Lindau disease, advanced papillary renal cell carcinoma, and penile cancer.
Updates in the Treatment of Secondary Acute Myeloid Leukemia
This video reviews the biology of secondary acute myeloid leukemia and highlights some of the latest findings in the treatment of this disease.
Is One Immunotherapy for Lung Cancer Better Than the Rest?
This video reviews immunotherapy options now available for the treatment of lung cancer across different lines of therapy.
Treating Prostate Cancer in Older Patients
This video reviews the management approach for prostate cancer in older patients, including when screening is appropriate and how geriatric assessments can guide treatment decisions.
Abemaciclib Shows Activity for HR-Positive Breast Cancer Brain Mets
This video examines an early trial studying abemaciclib for the treatment of brain metastases in patients with hormone receptor–positive, HER2-negative breast cancer.
Long-Term Data Confirm TH Benefit in Early HER2-Positive Breast Cancer
This video highlights 7-year follow-up data from the APT trial, which studied adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer.
Gemcitabine Maintenance in Lung Cancer Could Be Low Cost Alternative
This video highlights a study that tested an alternative maintenance strategy determined by response to induction chemotherapy for patients with advanced non-squamous non–small-cell lung cancer.
Could SBRT Have Role in Metastatic Kidney Cancer?
This video examines a pilot trial that tested stereotactic body radiotherapy plus nephrectomy in patients with renal cell carcinoma.
SUNSHINE: High-Dose Vitamin D Improved PFS in Colorectal Cancer
This video highlights results of the SUNSHINE study, which found that high-dose vitamin D added to standard treatment slowed disease progression in newly diagnosed metastatic colorectal cancer.
Treating Older Patients With Myeloma: Is Frailty More Important Than Age?
In this peer-to-peer discussion two experts discuss the nuances and challenges of treating elderly patients with myeloma, and why therapies need to be tailored based on frailty status rather than age.
US Could Save Nearly $1 Billion With Pembrolizumab Dosing Change
This video examines how a change to weight-based pembrolizumab dosing in first-line PD-L1–positive lung cancer could save nearly $1 billion in US healthcare costs.
Targeting IDH in Acute Myeloid Leukemia
This video examines the targeting of IDH1/IDH2 mutations in patients with relapsed or refractory acute myeloid leukemia.
ASCO 2017: Updates on HER2-Positive Breast Cancer Treatment
This video highlights the latest studies presented at the 2017 ASCO Annual Meeting on the treatment of HER2-positive breast cancer.
Marker in Prostate Cancer Fails to Predict Response to PARP Inhibition
This video examines clinical and genomics data from the NCI 9012 trial, which studied abiraterone combined with a PARP inhibitor in patients with metastatic castration-resistant prostate cancer.
Getting Older Cancer Patients on Clinical Trials
This video examines challenges and opportunities in getting older patients with cancer enrolled in clinical trials.
Role for Afatinib in p16-Negative Head and Neck Cancer?
This video reviews results of LUX-Head & Neck 2, a randomized phase III trial that studied afatinib as adjuvant therapy in patients with unresected squamous cell head and neck cancer.