
Opinion|Videos|February 14, 2025
Challenges in Treating Frail Patients With NDMM: In the Real-World Practice: Potential Steroid-Free Regimens
Panelists discuss how frailty assessment influences treatment decisions in patients with transplant-ineligible newly diagnosed multiple myeloma (NDMM), particularly examining the IFM2017-03 study’s evaluation of a dexamethasone-sparing approach using daratumumab plus lenalidomide in frail patients.
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Video content above is prompted by the following:
- How does frailty impact treatment outcomes in transplant-ineligible NDMM?
- What are your thoughts on the IFM2017-03 study evaluating a dexamethasone-sparing regimen with daratumumab plus lenalidomide in frail patients with NDMM?
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Related to this article

In a phase 2 trial, CD38-targeted immune-PET detected active multiple myeloma in some patients with no signs of disease on standard fluorodeoxyglucose PET/CT.
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