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Breast Cancer

Latest News

May 14th 2026

TIP113 HERTHENA-PanTumor01 (NCT06172478): Expansion of a Global Phase 2 Trial of HER3-DXd in Patients With Advanced/Metastatic HR+/HER2− Breast Cancer

By Funda Meric-Bernstam, MD, Christos Fountzilas, Izuma Nakayama

114 Comparing An AI-Based Prognostic Test With a 21-Gene Assay for Recurrence Prediction in Premenopausal Node-Positive HR+ HER2– Breast Cancer

By Jailan Elayoubi, Kathryn J. Ruddy, MD, MPH, Khalil Choucair

115 Evaluating an AI-Based Prognostic Test to Guide Adjuvant CDK4/6 Inhibitor Selection in Early HR+/HER2– Breast Cancer

By Nicholas McAndrew, Elena Diana Chiru, Aditya Bardia, MD, MPH, FASCO

116 Impact of Neoadjuvant Chemotherapy (NACT) Response on Clinical Outcomes With Ribociclib (RIB) in HR+/HER2− EBC: A Subgroup Analysis From the Phase 3 NATALEE Trial

By Nicholas McAndrew, Stephen Chia, Fabio Puglisi

117 Risk of Recurrence (ROR) Among Patients With HR+/HER2− Early Breast Cancer (EBC) Involving 1-3 Axillary Lymph Nodes (N1): A Real-World Evaluation

By Pedram Razavi, Joyce O’Shaughnessy, MD, Lasika Seneviratne, MD

Video Series

Expert in oncology

Circulating Tumor DNA: Future Directions in Care

Expert in oncology

Considering Real-World Applications With ctDNA

Expert in oncology

Impact of ctDNA on the Management of Breast Cancer

Expert in oncology

Scenario 2: Use of ctDNA to Monitor High-Risk TNBC

Expert in oncology

Nuancing the Benefit of Circulating Tumor DNA

Expert in oncology

Clinical Trial Data on Use of ctDNA Assays

Expert in oncology

Identifying Use of ctDNA Across Tumor Types

Expert in oncology

Understanding the Mechanisms and Use of ctDNA and MRD Testing

Role of Neurooncologists in Management of HER2+ Breast Cancer and Brain Metastases

Role of Neurooncologists in Management of HER2+ Breast Cancer and Brain Metastases

Trastuzumab Deruxtecan Treatment for Metastatic HER2+ Breast Cancer with Brain Metastases

Trastuzumab Deruxtecan Treatment for Metastatic HER2+ Breast Cancer with Brain Metastases

Latest Videos

The Impact of GLP-1–Mediated Weight Loss on Mammographic Density and Radiomic Risk

The Impact of GLP-1–Mediated Weight Loss on Mammographic Density and Radiomic Risk

Lessons From the Withdrawal of Atezolizumab in Metastatic TNBC

Lessons From the Withdrawal of Atezolizumab in Metastatic TNBC

How Has Immunotherapy Evolved in Breast Cancer Treatment?

How Has Immunotherapy Evolved in Breast Cancer Treatment?

Balancing Local Control With Long-Term Cosmesis in Re-Irradiation

Balancing Local Control With Long-Term Cosmesis in Re-Irradiation

Leveraging Human Nuance in the AI Era of Radiation Oncology

Leveraging Human Nuance in the AI Era of Radiation Oncology

Navigating Proton and Photon Techniques for Locoregional Recurrence

Navigating Proton and Photon Techniques for Locoregional Recurrence

Precision De-escalation and Sequencing in Modern Breast Radiation Oncology

Precision De-escalation and Sequencing in Modern Breast Radiation Oncology

Bridging the "Survivorship Cliff" After Radiotherapy for Breast Cancer

Bridging the "Survivorship Cliff" After Radiotherapy for Breast Cancer

Sequencing ADCs and Targeted Therapies With Radiation in Breast Cancer

Sequencing ADCs and Targeted Therapies With Radiation in Breast Cancer

Because there are so many options available for treating DCIS, the chosen method is often based upon the patients�’ preferences, said Jean L. Wright, MD, FASTRO.

What to Consider After Diagnosing a Patient With Ductal Carcinoma In Situ

Shorts

Managing Immunotherapy-Related Toxicities in Breast Cancer

Managing Immunotherapy-Related Toxicities in Breast Cancer

3 months ago

by

Sarah Poland, MD

Can Preoperative Radiation Help Patients Skip Breast Cancer Surgery?

Can Preoperative Radiation Help Patients Skip Breast Cancer Surgery?

3 months ago

by

Parul Barry

How AI Is Revolutionizing Electronic Health Records

How AI Is Revolutionizing Electronic Health Records

3 months ago

by

Sunil W. Dutta, MD

Patrick Borgen, MD, discussed the impact that MRD and ctDNA have played on treatment selection for breast cancer, particularly regarding surgery.

Examining the Impact of ctDNA on Breast Cancer Surgery

3 months ago

by

Patrick I. Borgen, MD

Why Survivorship is the Next Phase of Cancer Research

Why Survivorship is the Next Phase of Cancer Research

3 months ago

by

Fumiko Chino, MD

Personalizing Diet Based on Patient Risk and Metabolism

Personalizing Diet Based on Patient Risk and Metabolism

4 months ago

by

Ifeoma Dikeocha, PhD

The Missing Link in Cancer Research: Diversity

The Missing Link in Cancer Research: Diversity

4 months ago

by

Kathie-Ann Joseph, MD, MPH, FACS

Revolutionizing Breast Cancer: From 7 Weeks to 1 Week of Radiation

Revolutionizing Breast Cancer: From 7 Weeks to 1 Week of Radiation

4 months ago

by

Parul Barry

Beyond Mastectomy: The Power of Oncoplastic Surgery

Beyond Mastectomy: The Power of Oncoplastic Surgery

4 months ago

by

Kathie-Ann Joseph, MD, MPH, FACS

The Complex Decisions in Treating DCIS Breast Cancer

The Complex Decisions in Treating DCIS Breast Cancer

4 months ago

by

Jean L. Wright, MD, FASTRO

Podcasts

Neil M. Iyengar, MD, spoke about the potential impact of exercise on patient-reported outcomes in cancer and achieving work-life balance.

Finding a Place for Exercise Oncology in the Treatment of Breast Cancer

Sarah Donahue, MPH, NP, speaks to the importance of communicating potential adverse effects associated with treatments such as CDK4/6 inhibitors to patients with breast cancer.

January 15, 2024

Managing CDK4/6 Inhibitor, ADC Toxicity in Metastatic Breast Cancer

HER2CLIMB-02 Trial Shows ‘Interesting Data’ in HER2+ Breast Cancer

January 8, 2024

HER2CLIMB-02 Trial Shows ‘Interesting Data’ in HER2+ Breast Cancer

Combining anastrozole with palbociclib, trastuzumab, and pertuzumab as a frontline therapy for hormone receptor–positive, HER2-positive breast cancer may avoid some of the toxicities associated with chemotherapy, says Amy Tiersten, MD.

January 1, 2024

Frontline Chemo-Free Regimen Supported in HR+/HER2+ Breast Cancer Therapy

Early screening for breast cancer may help match patients with appropriate systemic therapies depending on the extent of their tumors, according to Rakhshanda Rahman, MD, FRCS, FACS.

December 18, 2023

Expert Discusses Screening Advocacy, AI, and Developments in Breast Cancer

Rebecca M. Shulman, MD, and Zachary Kiss, DO, discuss findings from a study evaluating differences in outcomes with radiotherapy and disease characteristics of patients with breast cancer harboring BRCA mutations compared with those without mutated disease.

October 30, 2023

Experts Discuss Differences in Radiotherapy Outcomes in BRCA+ Breast Cancer

Rakhshanda Rahman, MD, FRCS, FACS, emphasizes educating patients and physicians on the potential risks and benefits of new approaches and technologies involved in the de-escalation of breast cancer treatment.

Oncology On-The-Go Podcast: De-escalating Breast Cancer Treatment

Minh-Tri Nguyen, MD, spoke with CancerNetwork® about differences between time to treatment, socioeconomic status, and clinical outcomes in rural and urban patients with breast cancer.

February 27, 2023

Oncology On-The-Go Podcast: Time to Treatment for Breast Cancer in Rural Populations

Experts from Emory Winship Cancer Institute discuss how the FDA approval of sacituzumab govitecan will impact the treatment of breast cancer.

February 20, 2023

Oncology On-the-Go Podcast: Sacituzumab Govitecan for HR+/HER2– Advanced Breast Cancer

Yancey Warren, Jr, MD, MAT, and Lejla Hadzikadic-Gusic, MD, MSc, spoke with CancerNetwork® about their work investigating the use of integrative oncology services among young patients diagnosed with breast cancer.

January 16, 2023

Oncology Peer Review On-The-Go: Integrative Oncology in Young Population with Breast Cancer

CME Content

19th Annual New York GU Cancers Congress®

19th Annual New York GU Cancers Congress®

Maha Hussain, MD, FACP, FASCO; Daniel P. Petrylak, MD

Go to PER in Chicago

In-Person + Virtual Event

Go to PER in Chicago

May 29-31, 2026

Community Oncology Connections™: Beyond Primary End Points – Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | Tennessee Oncology Practice Society

Community Oncology Connections™: Beyond Primary End Points – Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | Tennessee Oncology Practice Society

Seth A. Wander, MD, PhD; Kamel Abou Hussein, MD

Iowa Oncology Society

Iowa Oncology Society

1 Session is Available!

Community Oncology Connections™: Beyond Primary End Points – Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | Nevada Oncology Society

Community Oncology Connections™: Beyond Primary End Points – Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | Nevada Oncology Society

Seth A. Wander, MD, PhD; Ruta D. Rao, MD

Community Oncology Connections™: Beyond Primary End Points – Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | The Arizona Clinical Oncology Society

Community Oncology Connections™: Beyond Primary End Points – Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | The Arizona Clinical Oncology Society

Marla D. Lipsyc-Sharf, MD; Richard Zelkowitz, MD

Community Oncology Connections™: Beyond Primary End Points – Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | Missouri Oncology Society

Community Oncology Connections™: Beyond Primary End Points – Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer | Missouri Oncology Society

Seth A. Wander, MD, PhD; Kate Baxstrom, MD

Kansas Society of Clinical Oncology

Kansas Society of Clinical Oncology

1 Session is Available!

A Case-Guided Discussion on Managing Immune Thrombocytopenic Purpura (ITP)

A Case-Guided Discussion on Managing Immune Thrombocytopenic Purpura (ITP)

Cindy Neunert, MD, MSCS; Hanny Al-Samkari, MD; Joseph Shatzel, MD, MCR

Louisiana Oncology Society

Louisiana Oncology Society

1 Session is Available!

Missouri Oncology Society

Missouri Oncology Society

1 Session is Available!

New Mexico Society of Clinical Oncology

New Mexico Society of Clinical Oncology

1 Session is Available!

Medical Crossfire®: Integrating Next-Generation Endocrine Targeting Therapies to Improve Outcomes for Patients With HR+/HER2- Breast Cancer

Medical Crossfire®: Integrating Next-Generation Endocrine Targeting Therapies to Improve Outcomes for Patients With HR+/HER2- Breast Cancer

William J. Gradishar, MD, FASCO, FACP; Laura Huppert, MD; Yuan Yuan, MD, PhD

$Cases and Conversations™: Sorting Through the Expanding Treatment Options for Patients with Relapsed/Refractory Multiple Myeloma$

Cases and Conversations™: Sorting Through the Expanding Treatment Options for Patients with Relapsed/Refractory Multiple Myeloma

C. Ola Landgren, MD, PhD; Mohamad Mohty, MD, PhD; Surbhi Sidana, MD

Evolving Treatment Strategies in Pancreatic Cancer: Current Standards, Emerging Targets, and the Role of Molecular Testing

Evolving Treatment Strategies in Pancreatic Cancer: Current Standards, Emerging Targets, and the Role of Molecular Testing

Eileen M. O’Reilly, MD; E. Gabriela Chiorean, MD, FASCO; Michael J. Pishvaian, MD, PhD; Brian Wolpin, MD, MPH

Medical Crossfire®: Expert Perspectives on Targeting c-Met Overexpression and 𝘔𝘌𝘛 Genomic Alterations in NSCLC – Unveiling the Complexities of 𝘔𝘌𝘛 Dysregulation

Medical Crossfire®: Expert Perspectives on Targeting c-Met Overexpression and 𝘔𝘌𝘛 Genomic Alterations in NSCLC – Unveiling the Complexities of 𝘔𝘌𝘛 Dysregulation

Rebecca Heist, MD, MPH; Alex A. Adjei, MD, PhD, FACP; Sandip Patel, MD, FASCO; Jeremy Segal, MD, PhD

GI Tumor Board—Applying Recent Advances in Biomarker Testing and Treatment in Metastatic Colorectal Cancer

GI Tumor Board—Applying Recent Advances in Biomarker Testing and Treatment in Metastatic Colorectal Cancer

John H. Strickler, MD; Stacey A. Cohen, MD; Aparna Parikh, MD; Kanwal P.S. Raghav, MBBS, MD

Cases & Conversations™: Transforming AML Care—Precision Strategies, Evolving Therapies, and Clinical Insights

Cases & Conversations™: Transforming AML Care—Precision Strategies, Evolving Therapies, and Clinical Insights

Gail J. Roboz, MD; Hagop Kantarjian, MD; Catherine Lai, MD, MPH; Amer Zeidan, MBBS, MHS

Tumor Board: Expert Insights on Managing Classical 𝘌𝘎𝘍𝘙 Mutations, 𝘌𝘎𝘍𝘙 Exon 20 Insertions, and Atypical 𝘌𝘎𝘍𝘙 Mutations in Metastatic NSCLC

Tumor Board: Expert Insights on Managing Classical 𝘌𝘎𝘍𝘙 Mutations, 𝘌𝘎𝘍𝘙 Exon 20 Insertions, and Atypical 𝘌𝘎𝘍𝘙 Mutations in Metastatic NSCLC

Balazs Halmos, MD, MS; Enriqueta Felip, MD, PhD; Julia Rotow, MD

Medical Crossfire®: Improving Patient Outcomes in Myeloproliferative Neoplasms With Novel Therapeutic Approaches

Medical Crossfire®: Improving Patient Outcomes in Myeloproliferative Neoplasms With Novel Therapeutic Approaches

Rami Komrokji, MD; Gabriela Hobbs, MD; John Mascarenhas, MD; Naveen Pemmaraju, MD

Medical Crossfire®: Precision Medicine in Glioma Treatment — Integration of Molecular Profiling to Inform Targeted Therapies

Medical Crossfire®: Precision Medicine in Glioma Treatment — Integration of Molecular Profiling to Inform Targeted Therapies

Vinay K. Puduvalli, MD; Manmeet Ahluwalia, MD, MBA; Stephen J. Bagley, MD, MSCE; Angela Waanders, MD, MPH, MS

PER Tumor Board®: Applying Recent Advances to Transform the Treatment Paradigm in SCLC—Expert Perspectives on New Approvals and Emerging Strategies

PER Tumor Board®: Applying Recent Advances to Transform the Treatment Paradigm in SCLC—Expert Perspectives on New Approvals and Emerging Strategies

Jonathan W. Goldman, MD; Percy Lee, MD, FASTRO; Erminia Massarelli, MD, PhD, MS; Misty D. Shields, MD, PhD

Medical Crossfire®: Harnessing the Power of Modern Therapies in Newly Diagnosed Multiple Myeloma

Medical Crossfire®: Harnessing the Power of Modern Therapies in Newly Diagnosed Multiple Myeloma

C. Ola Landgren, MD, PhD; Mohamad Mohty, MD, PhD; Surbhi Sidana, MD

Wisconsin Association of Hematology and Oncology

Wisconsin Association of Hematology and Oncology

1 Session is Available!

Indiana Oncology Society

Indiana Oncology Society

1 Session is Available!

Rhode Island Oncology Society

Rhode Island Oncology Society

2 Sessions are Available!

Breast Cancer Tumor Board: Targeting TROP2 – Innovations in Triple-Negative Breast Cancer Treatment

Breast Cancer Tumor Board: Targeting TROP2 – Innovations in Triple-Negative Breast Cancer Treatment

Joyce O’Shaughnessy, MD; Matthew P. Goetz, MD; Hope S. Rugo, MD, FASCO

Expert Guidance on Frequently Asked Questions Regarding the Use of ADCs in TNBC

Expert Guidance on Frequently Asked Questions Regarding the Use of ADCs in TNBC

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Virginia Kaklamani, MD, DSc

Establishing the Rationale for ADC and ICI Combinations in TNBC

Establishing the Rationale for ADC and ICI Combinations in TNBC

Virginia Kaklamani, MD, DSc; Tiffany A. Traina, MD, FASCO

Breaking Down the Rationale for Targeting TROP2 in TNBC

Breaking Down the Rationale for Targeting TROP2 in TNBC

Filipa Lynce, MD; Rita Nanda, MD

Dissecting Clinical Trial and Real-World Data for ADCs in TNBC

Dissecting Clinical Trial and Real-World Data for ADCs in TNBC

Filipa Lynce, MD; Rita Nanda, MD

Evaluating the Latest Data and Ongoing Trials for Novel ADC Approaches in TNBC

Evaluating the Latest Data and Ongoing Trials for Novel ADC Approaches in TNBC

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD

Breaking Down the Latest Clinical Data for First-line Maintenance and R/R SCLC

Breaking Down the Latest Clinical Data for First-line Maintenance and R/R SCLC

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Hossein Borghaei, DO, MS

Broadening the Frontline—Studies Informing the Use of Immunotherapy in Hepatocellular Carcinoma

Broadening the Frontline—Studies Informing the Use of Immunotherapy in Hepatocellular Carcinoma

Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

Cross-Disease Integration of Immunotherapy Innovations

Cross-Disease Integration of Immunotherapy Innovations

Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

Optimizing Treatment for Biliary Tract Cancers

Optimizing Treatment for Biliary Tract Cancers

Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Virginia Kaklamani, MD, DSc; Filipa Lynce, MD; Rita Nanda, MD; Tiffany A. Traina, MD, FASCO

Expert Roundtable and Panel Discussions: Current and Future Landscape of TNBC

Expert Roundtable and Panel Discussions: Current and Future Landscape of TNBC

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Tiffany A. Traina, MD, FASCO

Practical Considerations and Future Directions for New Treatment Strategies in SCLC

Practical Considerations and Future Directions for New Treatment Strategies in SCLC

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Misty D. Shields, MD, PhD

Show Me the Data®: New and Emerging Roles for Oral SERD Therapy in the Treatment of ER+/HER2– Breast Cancer

Show Me the Data®: New and Emerging Roles for Oral SERD Therapy in the Treatment of ER+/HER2– Breast Cancer

Ana C. Garrido-Castro, MD; Pedram Razavi, MD, PhD

Navigating Treatment Gaps in SCLC: Relapse, Resistance, and Need for New Options

Navigating Treatment Gaps in SCLC: Relapse, Resistance, and Need for New Options

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Giannis Mountzios ΜD, PhD

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Jason Hafron, MD; Aaron D. Berger, MD; Arpeet Shah, MD

Imaging Matters: Decoding PSMA PET for Better Decision-Making

Imaging Matters: Decoding PSMA PET for Better Decision-Making

Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Scott T. Tagawa, MD, MS, FACP, FASCO

BURST CME™ Resource Center: Integrating Novel PSMA-Directed Radioligand Approaches for Diagnosis and Management of Prostate Cancer

BURST CME™ Resource Center: Integrating Novel PSMA-Directed Radioligand Approaches for Diagnosis and Management of Prostate Cancer

Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Nerina McDonald, MSPAS, PA-C; Scott T. Tagawa, MD, MS, FACP, FASCO

Ready for Radioligand Therapy? Patient Selection and Sequencing Simplified

Ready for Radioligand Therapy? Patient Selection and Sequencing Simplified

Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Scott T. Tagawa, MD, MS, FACP, FASCO

Working Together: Overcoming Barriers to Optimize Outcomes in Patients Treated With Radioligand Therapy Through Multidisciplinary Care

Working Together: Overcoming Barriers to Optimize Outcomes in Patients Treated With Radioligand Therapy Through Multidisciplinary Care

Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Nerina McDonald, MSPAS, PA-C; Scott T. Tagawa, MD, MS, FACP, FASCO

Radioligand Therapy 101: The Science Behind the Strategy

Radioligand Therapy 101: The Science Behind the Strategy

Jeremie Calais, MD, PhD; Tanya B. Dorff, MD; Scott T. Tagawa, MD, MS, FACP, FASCO

Community Practice Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy–Strategies for the Multidisciplinary Team

Community Practice Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy–Strategies for the Multidisciplinary Team

Yana G. Najjar, MD; Sapna Patel, MD

A New Era of Targeted Therapy for Advanced NSCLC: Exploring Future Directions for Bispecific Antibodies and ADCs

A New Era of Targeted Therapy for Advanced NSCLC: Exploring Future Directions for Bispecific Antibodies and ADCs

Sandip Patel, MD, FASCO; Myung-Ju Ahn, MD; Giannis Mountzios, MD, MSc, PhD; Zofia Piotrowska, MD, MHS

Advances in Managing EGFR-Mutant NSCLC: Applying Evidence Across the Disease Continuum

Advances in Managing EGFR-Mutant NSCLC: Applying Evidence Across the Disease Continuum

Tina Cascone, MD, PhD; Christina Baik, MD, MPH; David Planchard, MD, PhD

Navigating Advances in Neovascular Retinal Disease: Translating Evidence to Practice in AMD, DME, and RVO

Navigating Advances in Neovascular Retinal Disease: Translating Evidence to Practice in AMD, DME, and RVO

SriniVas R. Sadda, MD, FARVO; Mark R. Barakat, MD, FASRS; David A. Eichenbaum, MD, FASRS

Enhancing Prostate Cancer Outcomes – The Role of PSMA and Targeted Treatment Strategies

Enhancing Prostate Cancer Outcomes – The Role of PSMA and Targeted Treatment Strategies

Ana Kiess, MD, PhD; Erin Grady, MD, CCD, FACNM, FSNMMI; Himanshu Nagar, MD, MS; Scott T. Tagawa, MD, MS, FASCO, FACP

(CME Track) Antibody–Drug Conjugates in Oncology: The Essentials of AE Management for Better Patient Outcomes

(CME Track) Antibody–Drug Conjugates in Oncology: The Essentials of AE Management for Better Patient Outcomes

Michelle L. Taylor, ANP-BC; Emely Alfaro, DNP, RN, CNS, OCN; Paige Griffith, CRNP; Beth Sandy, MSN, CRNP, FAPO

Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Erminia Massarelli, MD, PhD, MS; Misty D. Shields, MD, PhD

Personalized Approaches in NSCLC: Early Detection, Molecular Testing, and Targeted Therapies

Personalized Approaches in NSCLC: Early Detection, Molecular Testing, and Targeted Therapies

Charu Aggarwal, MD, MPH, FASCO; Zofia Piotrowska, MD, MHS

9th Annual School of Nursing Oncology™

9th Annual School of Nursing Oncology™

Beth Faiman, PhD, MSN, APN-BC, BMTCN, AOCN, FAAN, FAPO; Beth Sandy, MSN, CRNP, FAPO; Lindsay Adkins, MSN, FNP-BC, BMTCN; Jeneth Aquino, DNP, FNP-BC; Casey Gormley, MSN, FNP-C, AOCNP; Heather J. Jackson, PhD, FNP-BC; Kelsey Martin, AG-ACNP-BC, AOCNP; Nerina T. McDonald, PA-C; Lauren Verity Moore, DNP, MSN, AGACNP-BC; Faith A. Mutale, DNP, CRNP; Tiffany Richards, PhD, ANP-BC, AOCNP; Emily Skotte, DNP, MSN, ACNP-BC; Leslie Smith, DNP, RN, APRN-CNS, AOCNS, BMTCN; Saneese Stephen, PA-C, MPAS; Sara M. Tinsley-Vance, PhD, APRN, AOCN

Community Practice Connections™: DLL3-Targeting Bispecific Antibodies for Small Cell Lung Cancer—From Innovation to Practice

Community Practice Connections™: DLL3-Targeting Bispecific Antibodies for Small Cell Lung Cancer—From Innovation to Practice

Jacob Sands, MD; Anne Chiang, MD, PhD

More News

118 Pooled Analysis of Patients Treated With 1st-Line (1L) Ribociclib (RIB) + Endocrine Therapy (ET) in the MONALEESA (ML) Studies: Long-Term Progression-Free Survival (PFS)

ByFabrice Andre,Peter A. Fasching,Aleix Prat,Patrick Neven, MD, PhD,Yen-Shen Lu,Aditya Bardia, MD, MPH, FASCO,Giuseppe Curigliano,Virginia Kaklamani, MD, DSc,Pedram Razavi,Yoon Sim Yap,Fei Su,Estelle Roux,Kristyn Pantoja,Jiwen Wu,Agnes Lteif,Dejan Juric

May 12th 2026

119 Progression-Free Survival (PFS) and Overall Survival (OS) Results From the Phase 3 MONALEESA-3 Trial of Postmenopausal Patients With Hormone Receptor–Positive (HR+)/Human Epidermal Growth Factor Receptor 2–Negative (HER2−) Advanced Breast Cancer (ABC) Treated With Ribociclib (RIB) + Fulvestrant (FUL): A Subgroup Analysis of Patients With Invasive Lobular Carcinoma (ILC)

ByMichelino De Laurentiis,Jason Mouabbi,Seock-Ah Im,Megan Kruse, MD,Stephen Chia,Sara Brucker,Cristian Villanueva,Guy Jerusalem,Melissa Gao,Gary Sopher,Jiwen Wu,Juan Pablo Zarate,J. Thaddeus Beck

May 11th 2026

121 Five-Year Analysis of Distant Disease-Free Survival (DDFS) Across Key Subgroups From the Phase 3 NATALEE Trial of Ribociclib (RIB) Plus a Nonsteroidal Aromatase Inhibitor (NSAI) in Patients With HR+/HER2− Early Breast Cancer (EBC)

BySara A. Hurvitz, MD,Michal Jarzab,Alistair Ring,Priyanka Sharma, MD,Ionut Temciuc,Huilin Hu,Murat Akdere,Juan Pablo Zarate,Denise A. Yardley, MD

May 10th 2026

123 Real-World Patient and Caregiver Experiences With Breast Cancer (BC) Risk of Recurrence (ROR) in the US: Results of an Online Survey and Social Media Analysis

ByHope S. Rugo, MD,Megan-Claire Chase,Megan Rutt,Mary Lou Smith,Sue Weldon,Emilie Pain,Gaurav Vadnerkar,Tamalika Sen,Shiva Padhi,Nimisha Nadimpalli,Liz Santarsiero,Corinth Auld,Nadia Harbeck, MD, PhD,Anees B. Chagpar

May 9th 2026

124 Real-World Progression-Free Survival 2 and Tumor Response of CDK4/6is + Aromatase Inhibitor in Patients With HR+/HER2– Metastatic Breast Cancer

ByHope S. Rugo, MD,Adam M. Brufsky, MD, PhD,Rachel M. Layman,Xianchen Liu,Benjamin Li,Lynn McRoy,Aaron B. Cohen,Melissa Estevez,Paul Cottu,Marc Thill,Giuseppe Curigliano

May 9th 2026

TIP125 ReDiscover-2, a Phase 3 Study of Zovegalisib (RLY-2608) + Fulvestrant Versus Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-Mutant HR+/ HER2- Breast Cancer Following Recurrence or Progression on or After Treatment With a CDK4/6 Inhibitor (Trial in Progress)

ByHope S. Rugo, MD,Cristina Saura,Komal Jhaveri,Carlos Barrios,Sherene Loi, MD, PhD,Frederik Marme,Francois Clement Bidard,Yeon Hee Park,Peter Schmid, MD,Sarah L. Sammons,Giuseppe Curigliano

May 8th 2026

TIP126 TroFuse-011: A Phase 3, Randomized, Open-Label Study of Sacituzumab Tirumotecan With or Without Pembrolizumab vs Treatment of Physician’s Choice for Previously Untreated Locally Recurrent Unresectable or Metastatic Triple-Negative Breast Cancer With PD-L1 Combined Positive Score <10

ByHope S. Rugo, MD,Peter Schmid, MD,Javier Cortés, MD,Toshimi Takano,Peter A. Fasching,Yeon Hee Park,Giampaolo Bianchini,Sandra Ximena Franco,Cynthia Villarreal-Garza,Olivier Tredan,Yongmei Yin,Romualdo Barroso-Sousa,Xuan Peng,Usha Malhotra, MD,Karen Lisa Smith,Aditya Bardia, MD, MPH, FASCO

May 8th 2026

TIP127 TroFuse-012: A Phase 3, Randomized Study of Adjuvant Sacituzumab Tirumotecan Plus Pembrolizumab Vs Treatment of Physician’s Choice in Participants With Triple-Negative Breast Cancer who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response at Surgery

ByHeather McArthur, MD, MPH,Rebecca Dent, MD,Rina Hui,Yeon Hee Park,Peter Schmid, MD,Jing Wei,Wilbur Pan,Usha Malhotra, MD,Javier Cortés, MD

May 7th 2026

128 TroFuse-032: a Phase 3, Randomized Study of Pembrolizumab Plus Sacituzumab Tirumotecan or Chemotherapy Followed by Pembrolizumab Plus Chemotherapy for Early-Stage Triple-Negative Breast Cancer or Hormone Receptor-Low–Positive/Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer

ByPeter Schmid, MD,Jing Wei,Francisco Beca, MD, MSc,Usha Malhotra, MD,Nadia Harbeck, MD, PhD

May 7th 2026

Bridging the Gap: Overcoming Institutional Barriers to Exercise Oncology

ByJennifer A. Ligibel, MD

May 7th 2026

There are reimbursement and infrastructure challenges in oncology care, with the need for systemic changes to provide patients with lifesaving behavioral interventions.

TIP 129 The Role of Vitamin D in CDK4/6 Inhibitor Therapy for Breast Cancer

ByLowell Hart,William Amick,Sadie E. Greene

May 6th 2026

Clearance of a novel AI platform may represent an important advance in personalizing treatments for patients with early-stage breast cancer.

FDA Clears AI Stratification Tool in HR+/HER2– Invasive Breast Cancer

May 6th 2026

Clearance of a novel AI platform may represent an important advance in personalizing treatments for patients with early-stage breast cancer.

Exercise Oncology: Beyond Weight Management in Cancer Care

ByJennifer A. Ligibel, MD

May 6th 2026

Results from the CHALLENGE trial showed that activity can reduce cancer recurrence for patients with colorectal, breast, and prostate cancers.

132 Characteristics and Treatments of Patients Receiving Two or More Lines of Treatment for Metastatic Triple-Negative Breast Cancer in the US Community Health Setting

ByBrian Stwalley,Katelyn Heim,Anandaroop Dasgupta,Julie Katz,Sabrina Meyers,Jason Beal,Christer Svedman,Kaitlyn L. Kane,Monika A. Izano

May 5th 2026

Weight Loss and Cancer Risk: How Much Weight Loss Needs to Occur?

ByJennifer A. Ligibel, MD

May 5th 2026

Jennifer A. Ligibel, MD, discussed the complex link between weight loss and cancer risk, exploring data from bariatric surgery and the emerging role of GLP-1s.

133 Racial Disparities in Biomarker Testing, Treatment Utilization, and Outcomes in Patients with Metastatic Triple-Negative Breast Cancer (mTNBC) in U.S. Community Practices

ByKatherine Sanchez,George Dranitsaris,Tayla Poretta,Julie Katz,Aaron Peevyhouse,Heather Neuhalfen,Lee Ann Dietz,Brian Stwalley,Katelyn Heim,Sibel Blau

May 4th 2026

TIP134 ELECTRA: An Open-Label, Multicenter, Phase 1b/2 Study of Elacestrant in Combination With Abemaciclib in Patients With Brain Metastasis From ER+/HER2– Breast Cancer

ByNuhad Ibrahim, MD,Eva Ciruelos Gil,Sung-Bae Kim,Nancy U. Lin, MD,Ahmad Awada,Alessandro Di Sanzo,Bartomeu Piza Vallespir,Tomer Wasserman,Erika P. Hamilton, MD

May 4th 2026

SLN Surgery Omission Does Not Increase Radiotherapy Use in Breast Cancer

ByAriana Pelosci

May 4th 2026

Patients with breast cancer who omitted sentinel lymph node surgery did not have an increased uptake in other forms of treatment like radiation therapy.

TIP136 ELEGANT: Elacestrant Versus Standard Endocrine Therapy (ET) in Women and Men With Node-Positive, Estrogen Receptor–Positive (ER+), HER2-Negative (HER2–), Early Breast Cancer (eBC) With High Risk of Recurrence in a Global, Multicenter, Randomized, Open-Label Phase 3 Study

ByAditya Bardia, MD, MPH, FASCO,Virginia Kaklamani, MD, DSc,Joyce O’Shaughnessy, MD,Peter Schmid, MD,J. Thaddeus Beck,Michelino De Laurentiis,Giuseppe Curigliano,Hope S. Rugo, MD,Carlos H. Barcenas,William J. Gradishar, MD,Michail Ignatiadis,David Cameron,Giulia Tonini,Simona Scartoni,Jennifer Crozier,Tomer Wasserman,Sara M. Tolaney, MD, MPH

May 3rd 2026

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