SPOTLIGHT -
Can Vitamin D Serve as a Potential Biomarker for Thyroid Cancer?
Vitamin D deficiency may be a negative prognostic indicator for papillary thyroid cancer, according to the results of a recent retrospective study.
Certain Factors Associated With Decreased QOL in Thyroid Cancer Survivors
A recent study in Surgery found that thyroid cancer survivors reported increased complications related to surgery and radioactive iodine ablation.
Thyroidectomy Still Popular Despite Less Aggressive Treatment Recommendations
A recent study evaluated the impact of recommendations encouraging less aggressive lobectomy for patients with small papillary thyroid cancers.
Effect of Shorter Dose Interruption in Radioiodine-Refractory Differentiated Thyroid Cancer
Researchers evaluated the impact of dose interruption on survival for lenvatinib vs placebo in patients with progressive differentiated thyroid cancer.
Is Vitamin D Deficiency a Risk Factor for Thyroid Cancer?
A meta-analysis looked at the controversial link between decreased serum 25-hydroxyvitamin D levels and incidence of thyroid cancer.
Is NIFTP Truly a Non–Thyroid Cancer Diagnosis?
According to the American Thyroid Association guidelines, noninvasive follicular thyroid neoplasm with papillary-like features is benign.
Assessing Quality of Life After Thyroidectomy
Researchers evaluated the incidence of physical, psychological, and lifestyle effects among patients with differentiated thyroid cancer.
A 45-Year-Old With a Thyroid Gland Mass
A 45-year-old man presents with neck pain and a mass in the thyroid gland. What is your diagnosis?
Study Investigates Survival Rates in Patients with Medullary Thyroid Carcinoma
Researchers conducted the first population-based study of an unselected MTC cohort compared with the general population.
Utilizing US Features and BRAFV600E Mutation Status to Stratify Papillary Thyroid Carcinoma
Clinicians may be able to utilize this information as an effective preoperative tool to stratify risk and determine an initial surgical approach for patients with PTC.
Fukushima Screening Program Sheds Light on Pediatric Thyroid Cancer
The thyroid screening program put in place after the 2011 Fukushima Daiichi nuclear power station accident resulted in the diagnosis of a number of pediatric thyroid cancers.
Sizing Up Ultrasound-Based Risk-Stratification Systems for Thyroid Nodules
The performance of three international guidelines in detecting thryoid cancer was compared based on their sensitivity and fine-needle aspiration rates.
Do Larger Thyroid Tumors Mean Higher Rates of Malignancy and False-Negative FNA Results?
The authors looked at whether rates of malignancy and false-negative fine-needle aspiration results are heightened in large thyroid nodules.
The Verdict on IMRT Plus Doxorubicin in Unresectable Thyroid Cancer
A study in Thyroid evaluated the safety and efficacy of concurrent intensity-modulated radiation therapy and doxorubicin in thyroid cancer.
New Study Looks at Selumetinib for Treating Differentiated Thyroid Cancer
Interim results are in from a study evaluating whether adding selumetinib to RAI improves complete response, irrespective of MAPK pathway alterations.
Age, Lymph Node Positivity Link in Thyroid Cancer
A new study in Cancer Management and Research found a correlation between the age of patients with papillary thyroid cancer and lymph node positivity.
New Breakthrough Therapy Designated for Thyroid Cancer and NSCLC
LOXO-292, which selectively targets RET and has demonstrated preclinical activity against activating RET fusions/mutations, holds promise.
Eighth Edition of AJCC/TNM Staging System Best at Detecting Survival in Thyroid Cancer
The eighth edition outperforms the seventh edition in predicting survival differences in patients with papillary thyroid cancer and follicular thyroid cancer.
Male Sex Ups Mortality Risk in BRAF V600E Papillary Thyroid Cancer
The study confirmed a significant effect of male sex on PTC-specific patient survival in individuals with the most frequent oncogenic mutation.
Does Radioactive Iodine Post Reoperation Improve Thyroid Cancer Outcomes?
A study shows that receipt of radioactive iodine after reoperation may not be associated with improved outcomes.
Researchers Call for More Conservative Treatment of Small Thyroid Cancers
The steep increase in thyroid cancer diagnosis has not been mirrored by increasing mortality rates and is likely due to widespread overdiagnosis of small neoplasms.
Benefit From Treatment by High-Volume Surgeons in Advanced Papillary Thyroid Cancer?
Korean investigators concluded that, in terms of recurrence risk, a qualified high-volume surgeon may be optimal for performing the initial surgery in this setting.
Could Leukocyte DNA Methylation Patterns Inform Treatment of Thyroid Cancer?
Brazilian researchers say their study results “suggest the overall DNA methylation profile may be influenced by the histological subtype of thyroid cancer.”
Perspectives on Overdiagnosis, Overtreatment of Subclinical Thyroid Cancers
In an exclusive interview, thyroid cancer expert and surgeon Dr. Louise Davies discusses overdiagnosis and overtreatment of subclinical thyroid cancers.
Next-Gen Sequencing May Advance Tx of Patients With Poorly Differentiated Thyroid Cancer
Next-generation sequencing may prove to be a useful tool in the identification of co-mutations associated with resistance, an MD Anderson study suggests.
CVD Risk Factors Identified in Male Thyroid Cancer Survivors
In the Utah Cancer Survivors Study, male thyroid cancer survivors had an almost 50% higher risk of developing cardiovascular disease than females.
Will Large Gene Study Help to Personalize Thyroid Cancer Tx?
The study is potentially a “leap forward” in cancer genomics, particularly for subsets of patients with metastatic and anaplastic thyroid cancer.
Dabrafenib/Trametinib Approved for BRAF-Positive Anaplastic Thyroid Cancer
The approval should have a profound impact on patients with the rare tumor, according to experts.
RCC Agent Lenvatinib of Benefit in Anaplastic Thyroid Cancer
Certain genetic alterations associated with anaplastic transformation in thyroid cancer made patients sensitive to the multikinase inhibitor lenvatinib.
Cabozantinib Shows Strong Activity in RAI-Refractory Thyroid Cancer
Cabozantinib showed significant antitumor activity in the treatment of differentiated thyroid cancer that progressed following surgery and radioactive iodine therapy, according to a new phase II study.