PEG-Hemoglobin Trial Underway

Publication
Article
Oncology NEWS InternationalOncology NEWS International Vol 5 No 8
Volume 5
Issue 8

PISCATAWAY, NJ--Enzon, Inc. has begun a multidose, multicen-ter clinical trial of its hemoglobin-based oxygen carrier, PEG-hemoglobin, in cancer patients receiving radiation therapy. The agent was developed as a radiosensitizer to increase oxygenation of hypoxic tumors cells that may be resistant to irradiation. Patients will receive once-a-week infusions of PEG-hemoglobin followed by 5 days of radiation therapy, repeated weekly for 3 weeks.

PISCATAWAY, NJ--Enzon, Inc. has begun a multidose, multicen-terclinical trial of its hemoglobin-based oxygen carrier, PEG-hemoglobin,in cancer patients receiving radiation therapy. The agent wasdeveloped as a radiosensitizer to increase oxygenation of hypoxictumors cells that may be resistant to irradiation. Patients willreceive once-a-week infusions of PEG-hemoglobin followed by 5days of radiation therapy, repeated weekly for 3 weeks.

Articles in this issue
Chemo Improves Pain Relief in Advanced Prostate Cancer
Multimedia Computer Program Patiently Answers Young Cancer Patients' Questions
NCCR Urges Congress to Support Senate Bill for Cancer Research
Researchers Propose New Treatment Guidelines for HIV
Salvage Cryotherapy for Prostate Cancer Studied at M.D. Anderson
FNA Dropped From RDOG Study Due To High Rate of Insufficient Samples
New Thinking on HIV Progression Leads to New Strategies
Hospitals Told Not to Capitate for 'Wrong' Reasons
More Study Needed of Possible Carcinogenesis of Winter Gas Additive
President Makes NCAB Appointments
Algorithm Identifies Women at Risk of Ovarian Cancer
Three Million a Year Die From Tobacco-Related Causes
Marketing of Cancer Services Must Include All Payer Modalities
Dr. Kessler Corrects Misapprehension That The FDA Cannot Regulate Tobacco Products
New Surgical Techniques May Reduce Impotence, Incontinence
Related Videos
Artificial intelligence models may be “seamlessly incorporated” into clinical workflow in the management of prostate cancer, says Eric Li, MD.
Panelists smiling at camera on a blue background.
Panelists smiling at camera on a blue background.
Robust genetic testing guidelines in the prostate cancer space must be supported by strong clinical research before they can be properly implemented, says William J. Catalona, MD.
Treatment with tisotumab vedotin may be a standard of care in second- or third-line recurrent or metastatic cervical cancer, says Brian Slomovitz, MD, MS, FACOG.
A panel of 4 experts on multiple myeloma seated at a long table
A panel of 4 experts on multiple myeloma seated at a long table
Teresa Macarulla, MD, PhD, and Cindy Neuzillet, MD, PhD, experts on NRG1 fusion-positive malignancies
Teresa Macarulla, MD, PhD, and Cindy Neuzillet, MD, PhD, experts on NRG1 fusion-positive malignancies
Teresa Macarulla, MD, PhD, and Cindy Neuzillet, MD, PhD, experts on NRG1 fusion-positive malignancies
Related Content
More than half of the patients with non–muscle-invasive bladder cancer in the BOND-003 trial achieve a complete response at 6 months following treatment with cretostimogene grenadenorepvec.

Cretostimogene Grenadenorepvec Yields Durable Responses in NMIBC

December 1st 2023
Article

More than half of the patients with non–muscle-invasive bladder cancer in the BOND-003 trial achieve a complete response at 6 months following treatment with cretostimogene grenadenorepvec.

Personalized therapy tailored for mutation status is something to expect in the coming years for colorectal cancer treatment, notes Tanios S. Bekaii-Saab, MD.

Tanios S. Bekaii-Saab, MD, Speaks to Expanding Horizons in CRC Treatment

November 27th 2023
Podcast

Personalized therapy tailored for mutation status is something to expect in the coming years for colorectal cancer treatment, notes Tanios S. Bekaii-Saab, MD.

Surgery following treatment with checkpoint inhibitors yields no surgical complications in a cohort of patients with advanced renal cell carcinoma, according to Jason Scovell, MD.

Durvalumab/Tremelimumab/Surgery Appears Safe in Renal Cell Carcinoma

November 30th 2023
Article

Surgery following treatment with checkpoint inhibitors yields no surgical complications in a cohort of patients with advanced renal cell carcinoma, according to Jason Scovell, MD, PhD.

New treatment updates could help find more patient subtypes to target and treat in the world of CRC.

Multidisciplinary Care and New Treatment Options in CRC

November 20th 2023
Podcast

New treatment updates could help find more patient subtypes to target and treat in the world of CRC, according to Kristen K. Ciombor, MD, MSCI.

Realigning value-based models to increase reimbursement for hypofractionated radiotherapy in prostate cancer may minimize barriers to access among underserved communities.

Data Show Short-Course Radiotherapy Increase in Prostate Cancer

November 30th 2023
Article

Realigning value-based models to increase reimbursement for hypofractionated radiotherapy in prostate cancer may minimize barriers to access among underserved communities.

Investigators are assessing BI 764532 in extensive-stage small cell lung cancer and other neuroendocrine carcinoma as part of the phase 2 DAREON-5 study.

BI 764532 Earns FDA FTD in Large Cell Lung Neuroendocrine Carcinoma

November 29th 2023
Article

Investigators are assessing BI 764532 in extensive-stage small cell lung cancer and other neuroendocrine carcinoma as part of the phase 2 DAREON-5 study.