Ongoing Trials Aim to Determine Best Regimen for Transplant-Ineligible Patients With Myeloma
March 1st 2023Luciano J. Costa, MD, PhD, discussed additional studies evaluating various treatment regimens for transplant-ineligible patients with newly diagnosed multiple myeloma, aiming to determine the best standard in this population.
GRIFFIN Trial Supports Use of Dara-VRd in Transplant-Eligble Patients With Myeloma
February 28th 2023Luciano J. Costa, MD, PhD, discussed the results from the phase 2 GRIFFIN study, designed to evaluate the combination of daratumumab, bortezomib, lenalidomide, and dexamethasone in transplant-eligible patients with multiple myeloma.
Mediterranean Diet Correlates With Responses to Melanoma Immunotherapy
February 28th 2023Previous research has identified a link between nutrients commonly found in a Mediterranean diet such as fiber, unsaturated fats, antioxidants, and polyphenols, and immunomodulatory/anti-tumor activities, according to a dietician from the University of Groningen.
MAIA trial Supports Use of D-Rd in Transplant-Ineligible Patients With Myeloma
February 27th 2023Luciano J. Costa, MD, PhD discussed updating findings from the phase 3 MAIA trial of the triplet combination of daratumumab, lenalidomide, and dexamethasone in transplant-ineligible patients with newly diagnosed multiple myeloma.
Genomic Analysis Yields ‘Hypothesis Generating’ Data in Bladder Cancer Subtype
February 26th 2023An expert from Chase Comprehensive Cancer Center discusses how findings from a genomic analysis of the phase 2 BLASST-1 trial may identify biomarkers of response and resistance to nivolumab/chemotherapy in muscle-invasive bladder cancer.
Experts Discuss SOC for Transplant-Eligible Newly Diagnosed Multiple Myeloma
February 24th 2023Current standard of care options in transplant-eligible, newly diagnosed multiple myeloma have been outlined in groundbreaking trials, of which a group of experts convened to discuss the best treatment options.
ctDNA May Replace Bone Marrow Exams in Multiple Myeloma, Expert Says
February 23rd 2023An expert from Stanford Medicine that the goal behind a study characterizing circulating tumor DNA and its predictive value is to eventually replace blood marrow exams with a blood draw for those with multiple myeloma.
Panobinostat Regimen Yields Benefit for R/R Myeloma After Frontline ASCT
February 23rd 2023Evidence from a matched pair comparison with a concurrent control cohort suggests that panobinostat plus gemcitabine, busulfan, and melphalan improves progression-free survival in those with relapsed or refractory multiple myeloma, especially after first transplant.
Glasgow Prognostic Score May Predict Atezolizumab/Chemo Outcomes in SCLC
February 22nd 2023A favorable Glasgow prognostic score appears to correlate with improved overall survival and progression-free survival following treatment with atezolizumab plus carboplatin and etoposide for small cell lung cancer.
Nivolumab Combo Yields PFS Benefit Regardless of PD-L1, c-MET status in RCC
February 21st 2023An ongoing exploratory biomarker analysis of the CheckMate 9ER trial set out to identify predictive biomarkers or a composite model of response of nivolumab/cabozantinib efficacy in advanced renal cell carcinoma.
TFS Improves With Nivolumab, Salvage Nivolumab in Advanced Renal Cell Carcinoma
February 21st 2023Results from cohort A of the HCRN GU16-260 trial showed treatment-free survival was enhanced in patients with advanced renal cell carcinoma who received nivolumab monotherapy plus salvage nivolumab and ipilimumab maintenance.