March 29th 2023
Co-editor-in-Chief Howard S. Hochster, MD, highlights the most exciting developments from the 2023 Gastrointestinal Cancer Symposium hosted by the American Society of Clinical Oncology (ASCO).
January 25th 2023
Many Patients with Anal Cancer Experienced Chemoradiation Therapy Interruption and NoncompletionMay 4th 2020
A recent study published in JAMA Oncology revealed that quality improvement initiatives are necessary to optimize treatment and lessen chemotherapy interruption and noncompletion rates among patients with squamous cell anal carcinoma.
Henry Adewoye, MD, on the Phase I Trial of COM701 in Advanced Solid TumorsApril 30th 2020
The study was presented at the American Association for Cancer Research (AACR) Annual Virtual Meeting 2020 and demonstrated encouraging preliminary antitumor activity with objective responses as a monotherapy and in combination with nivolumab.
Experts Issue Recommendations for Patients with Rectal Cancer During the COVID-19 PandemicApril 10th 2020
Leading cancer experts from across Europe issued an international expert consensus statement regarding radiotherapy treatment options for patients with rectal cancer during the COVID-19 pandemic.
FDA Grants Priority Review to Pembrolizumab Monotherapy for TMB-High TumorsApril 7th 2020
The FDA granted priority review to pembrolizumab monotherapy for the treatment of adult and pediatric patients with unresectable or metastatic TMB-high solid tumors who have progressed following prior treatment and who have no satisfactory alternative treatment options.
Pembrolizumab Induces Significantly Improved PFS in MSI-H/dMMR Colorectal CancerApril 3rd 2020
The trial evaluating the first-line treatment of pembrolizumab in patients with microsatellite instability-high or mismatch repair deficient unresectable or metastatic colorectal cancer demonstrated improved PFS compared with chemotherapy.
Outcomes of the SARS-CoV-2 Infection in Patients with Cancer Treated in ChinaMarch 27th 2020
Researchers reported on the incidence and outcomes of the SARS-CoV-2 infection, which has been linked to COVID-19, in patients with cancer who were treated at a tertiary cancer institution in Wuhan, China.
Potential for Prognostic Biomarkers in T1 Colorectal Cancer Treatment SelectionMarch 23rd 2020
In this study, researchers found that endoscopic therapy was the most effective strategy for patients with T1 CRC with less aggressive biomarker profiles and laparoscopic colectomy was the most effective for patients with more aggressive profiles.
Early-Onset Gastric Cancer Suggested to be Genetically and Clinically DistinctJanuary 20th 2020
Incidence of early-onset gastric cancer has steadily increased in the US, now comprising >30% of new gastric cancer cases today, causing researchers to try and discover what makes this disease type unique.
Review of Maintenance Treatment in mCRC Highlights Need for Shared Decision MakingJanuary 16th 2020
Although researchers determined which regimen was preferred among physicians in treating metastatic colorectal cancer, they found that shared decision-making should include observation as an acceptable option.
Locally Advanced Rectal Cancer, What is the Standard of Care?
A 39-year-old Hispanic male presented with complaints of mucous stools, loss of appetite, rectal bleeding and a 30-pound weight loss within the past several months.
FDA Approves Avapritinib for Resectable or Metastatic Gastrointestinal Stromal TumorJanuary 10th 2020
The FDA approved avapritinib for the treatment of adult patients with unresectable or metastatic gastrointestinal stromal tumor harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations.